E Cretney, A Shanker, H Yagita, MJ Smyth, TJ … - Immunology and cell …, 2006 - nature.com Recombinant, soluble TNF-related apoptosis-inducing ligand (TRAIL) is currently being developed
as a promising natural immune molecule for trial in cancer patients because it selectively induces
apoptosis in transformed or stressed cells but not in most normal cells. In cancer patients, ... Cited by 53 - Related articles - BL Direct - All 5 versions
G Zauli, P Secchiero - Cytokine and Growth Factor Reviews, 2006 - Elsevier TRAIL is a member of the tumor necrosis factor superfamily that interacts with an unusually complex
receptor system, comprising transmembrane (TRAIL-R1, -R2, -R3 and -R4) and soluble
(osteoprotegerin) receptors. TRAIL has received considerable attention because of the ... Cited by 54 - Related articles - All 15 versions
- ►onlinejacc.org Y Michowitz, E Goldstein, A Roth, A Afek, A … - Journal of the American …, 2005 - Elsevier Stable and vulnerable atherosclerotic human plaques and aortas from atherosclerotic mice were
assayed for the presence of TRAIL, and its inducibility was assayed by immunoblot and
real-time polymerase chain reaction on peripheral mononuclear cells incubated with ... Cited by 49 - Related articles - All 16 versions
QS Mi, D Ly, P Zucker, M McGarry, TL Delovitch - Diabetes, 2004 - Am Diabetes Assoc In nonobese diabetic (NOD) mice, a deficiency in the number and function of invariant natural
killer T-cells (iNKT cells) contributes to the onset of type 1 diabetes. The activation of CD1d-restricted
iNKT cells by α-galactosylceramide (α-GalCer) corrects these deficiencies and protects ... Cited by 32 - Related articles - BL Direct - All 4 versions
U Schaefer, O Voloshanenko, D Willen, H Walczak - Front Biosci, 2007 - bioscience.org The Tumor necrosis factor (TNF)-Related Apoptosis Inducing Ligand, TRAIL, has gained much
attention due to its specific anti-tumor potential without toxic side effects. TRAIL binds to a complex
receptor system. In humans there are two death-inducing receptors for TRAIL while only ... Cited by 34 - Related articles - View as HTML - All 2 versions
RA Mahmoud, SA el-Ezz, AS Hegazy - The Italian journal of …, 2004 - ncbi.nlm.nih.gov In the present study we measured interleukin-18 (IL-18) and tumour necrosis factor-alpha
(TNF-alpha) levels by enzyme linked immunosorbent assay (ELISA) in sera from 65 diabetic
[30 with type 1 insulin dependent diabetes mellitus (IDDM) and 35 with type 2 non-insulin ... Cited by 26 - Related articles - All 2 versions
- ►amjpathol.org X Yang, J Wang, C Liu, WE Grizzle, S Yu, S Zhang, S … - American Journal of …, 2005 - ASIP Rheumatoid arthritis synovial fibroblasts (RASFs) contribute to arthritic cartilage
degradation. Although RASFs are normally resistant to apoptosis, Apo2L/tumor necrosis
factor-related apoptosis-inducing ligand (TRAIL)-based gene therapy has been ... Cited by 17 - Related articles - BL Direct - All 8 versions
- ►asnjournals.org C Lorz, A Benito-Martin, A Boucherot, AC … - Journal of the American …, 2008 - Am Soc Nephrol Apoptotic cell death contributes to diabetic nephropathy (DN), but its role is not well
understood. The tubulointerstitium from DN biopsy specimens was microdissected, and expression
profiles of genes related to apoptosis were analyzed. A total of 112 (25%) of 455 cell ... Cited by 18 - Related articles - All 5 versions
- ►jimmunol.org TS Griffith, H Kazama, RL VanOosten, JK … - The Journal of …, 2007 - Am Assoc Immnol The decision to generate a productive immune response or immune tolerance following pathogenic
insult often depends on the context in which T cells first encounter Ag. The presence of apoptotic
cells favors the induction of tolerance, whereas immune responses generated with ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org S Hirata, H Matsuyoshi, D Fukuma, A … - The Journal of …, 2007 - Am Assoc Immnol We previously reported the protection from myelin oligodendrocyte glycoprotein (MOG)-induced
experimental autoimmune encephalomyelitis (EAE) by the adoptive transfer of genetically modified
embryonic stem cell-derived dendritic cells (ES-DC) presenting MOG peptide in the ... Cited by 16 - Related articles - BL Direct - All 5 versions
