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Scholar Results 1 - 10 of 11 citing Laychock: Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells. (0.10 sec) 

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in …

- physiology.org
MJ MacDonald, LA Fahien, LJ Brown, NM … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
The importance of mitochondrial biosynthesis in stimulus secretion coupling in
the insulin-producing -cell probably equals that of ATP production. In
glucose-induced insulin secretion, the rate of pyruvate carboxylation is ...
Cited by 60 - Related articles - All 4 versions

Biology of LPA in health and disease


S Sengupta, Z Wang, R Tipps, Y Xu - Seminars in Cell and Developmental Biology, 2004 - Elsevier
The functions of lysophosphatidic acid (LPA) can be broadly divided into two
classes: (1) physiological and (2) pathological roles. The role of LPA in
embryonic development can be seen as early as oocyte formation. It ...
Cited by 39 - Related articles - All 4 versions

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo …

- endojournals.org
WL Holland, SA Summers - Endocrine Reviews, 2008 - Endocrine Soc
Obesity and dyslipidemia are risk factors for metabolic disorders including
diabetes and cardiovascular disease. Sphingolipids such as ceramide and
glucosylceramides, while being a relatively minor component of the lipid ...
Cited by 29 - Related articles - All 7 versions

Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic …

- diabetesjournals.org
LD Mastrandrea, SM Sessanna, SG Laychock - Diabetes, 2005 - Am Diabetes Assoc
Sphingosine-1 phosphate (S1P) is a bioactive sphingolipid with the potential to
mobilize Ca 2+ , to inhibit apoptosis, and to promote mitogenesis. Sphingosine
kinase (SPHK) and S1P were characterized in INS-1 insulinoma cells and ...
Cited by 21 - Related articles - All 5 versions

Sphingosine 1-Phosphate Affects Cytokine-Induced Apoptosis in Rat Pancreatic Islet {beta}- …

- endojournals.org
SG Laychock, SM Sessanna, MH Lin, LD … - Endocrinology, 2006 - Endocrine Soc
Cytokines mediate pancreatic islet ß-cell apoptosis and necrosis, leading to
loss of insulin secretory capacity and type 1 diabetes mellitus. The cytokines,
IL-1ß and interferon- , induced terminal deoxynucleotidyl ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Novel regulatory roles for protein phosphatase-2A in the islet β cell


A Kowluru - Biochemical pharmacology, 2005 - Elsevier
Protein phosphorylation constitutes one of the key signaling steps in
physiological insulin secretion. The phosphorylation status of a given protein
represents the balance of the activities of protein kinases and ...
Cited by 14 - Related articles - All 4 versions

Sphingolipid signalling in the cardiovascular system: Good, bad or both?

- auburn.edu [PDF] 
AE Alewijnse, SLM Peters - European Journal of Pharmacology, 2008 - Elsevier
Sphingolipids are biologically active lipids that play important roles in
various cellular processes and the sphingomyelin metabolites ceramide,
sphingosine and sphingosine-1-phosphate can act as signalling molecules in ...
Cited by 13 - Related articles - All 4 versions

Human Islet Function Is Not Impaired by the Sphingosine-1-Phosphate Receptor Modulator …


W Truong, JA Emamaullee, S Merani, CC … - American Journal of Transplantation, 2007 - ccmjournal.org
Cited by 9 - Related articles - BL Direct - All 5 versions

Atrial Natriuretic Peptide Promotes Pancreatic Islet {beta}-Cell Growth and Akt/Foxo1a/ …


H You, SG Laychock - Endocrinology, 2009 - Endocrine Soc
The adult differentiated insulin-secreting pancreatic islet -cell experiences
slow growth. This study shows that atrial natriuretic peptide (ANP) stimulates
cell proliferation and [3H]thymidine incorporation in INS-1E ...
Related articles - All 2 versions

[CITATION] FTY720 has no negative impact on human islet function in vitro after exposure for 48 hours in …


W Truong, JA Emamaullee, S Merani, CC … - American Journal of Transplantation, 2007 - Blackwell Publishing Ltd
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