- ►diabetesjournals.org RN Kulkarni, MG Roper, G Dahlgren, DQ Shih, … - Diabetes, 2004 - Am Diabetes Assoc Mice with deletion of insulin receptor substrate (IRS)-1 (IRS-1 knockout [KO]
mice) show mild insulin resistance and defective glucose-stimulated insulin
secretion and reduced insulin synthesis. To further define the role of ... Cited by 65 - Related articles - BL Direct - All 4 versions
- ►endojournals.org HJ Goren, RN Kulkarni, CR Kahn - Endocrinology, 2004 - Endocrine Soc Transgenic mice phenotypes generally depend on the background strains used in
their creation. To examine the effects of genetic background on insulin
signaling, we analyzed glucose homeostasis in four inbred strains of mice ... Cited by 49 - Related articles - BL Direct - All 5 versions
M Ohsugi, C Cras-Meneur, Y Zhou, E Bernal- … - Journal of Biological Chemistry, 2005 - ASBMB Running Title: Multiple roles of insulin signaling in islet cells ... Reduced
Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals
Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, ... Cited by 37 - Related articles - All 5 versions
- ►endojournals.org Q Huang, S Bu, Y Yu, Z Guo, G Ghatnekar, M … - Endocrinology, 2007 - Endocrine Soc Increased apoptosis of pancreatic ß-cells plays an important role in the
occurrence and development of type 2 diabetes. We examined the effect of
diazoxide on pancreatic ß-cell apoptosis and its potential mechanism in ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►physiology.org MI Borelli, F Francini, JJ Gagliardino - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc We evaluated the possible autocrine modulatory effect of insulin on glucose
metabolism and glucose-induced insulin secretion in islets isolated from normal
hamsters. We measured 14 CO 2 and 3 H 2 O production from D-[U- 14 ... Cited by 9 - Related articles - BL Direct - All 4 versions
J Jimenez-Feltstrom, I Lundquist, S … - Regulatory peptides, 2004 - Elsevier The dose–response curves for glucose-stimulated insulin and C-peptide release
from isolated islets were practically identical: 0.05–0.1 nmol/l insulin
stimulated, 1–100 nmol/l had no effect, whereas concentrations ≥250 ... Cited by 9 - Related articles - All 3 versions
- ►physiology.org SM Katzman, MA Messerli, DT Barry, A … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The cells within the intact islet of Langerhans function as a metabolic
syncytium, secreting insulin in a coordinated and oscillatory manner in response
to external fuel. With increased glucose, the oscillatory amplitude is ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►physiology.org A Bertuzzi, S Salinari, G Mingrone - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc A mathematical model that represents the dynamics of intracellular insulin
granules in -cells is proposed. Granule translocation and exocytosis are
controlled by signals assumed to be essentially related to ATP-to-ADP ratio ... Cited by 6 - Related articles - BL Direct - All 5 versions
JD Rivas-Carrillo, N Navarro-Alvarez, A Soto … - Cell Transplantation, 2006 - ingentaconnect.com Printed in the USA. All rights reserved. ... Amelioration of Diabetes in Mice
After Single-Donor Islet Transplantation ... Using the Controlled Release of
Gelatinized FGF-2 ... Jorge David Rivas-Carrillo,* Nalu Navarro-Alvarez,* ... Cited by 4 - Related articles - BL Direct - All 5 versions
- ►nih.gov RM Snider, M Ciobanu, AE Rue, DE Cliffel - Analytica chimica acta, 2008 - Elsevier We have developed a multiwalled carbon nanotube/dihydropyran (MWCNT/DHP)
composite sensor for the electrochemical detection of insulin in a microfluidic
device. This sensor has been employed for physiological measurements of ... Cited by 3 - Related articles - All 4 versions
