P Dandona, A Aljada, A Bandyopadhyay - TRENDS in Immunology, 2004 - Elsevier Recent data have revealed that the plasma concentration of inflammatory mediators, such as
tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6), is increased in the insulin resistant
states of obesity and type 2 diabetes, raising questions about the mechanisms underlying ... Cited by 530 - Related articles - All 4 versions
P Trayhurn, IS Wood - British Journal of Nutrition, 2007 - Cambridge Univ Press White adipose tissue is now recognised to be a multifunctional organ; in addition to the central
role of lipid storage, it has a major endo- crine function secreting several hormones, notably leptin
and adiponectin, and a diverse range of other protein factors. These various pro- tein ... Cited by 539 - Related articles - BL Direct - All 11 versions
- ►sapo.pt [PDF] JP Bastard, M Maachi, C Lagathu, MJ Kim, M … - Eur Cytokine …, 2006 - john-libbey-eurotext.fr Auteur(s) : Jean-Philippe Bastard, Mustapha Maachi, Claire Lagathu, Min Ji Kim, Martine
Caron, Hubert Vidal, Jacqueline Capeau, Bruno Feve , Inserm U680, Faculté de Médecine Pierre
et Marie Curie, site Saint-Antoine, Université Pierre et Marie Curie, Paris 6 et Service de ... Cited by 264 - Related articles - All 7 versions
P Trayhurn - Acta Physiologica Scandinavica, 2005 - interscience.wiley.com White adipose tissue (WAT) is now recognized as a major endocrine and secretory organ, releasing
a wide range of protein factors and signals termed adipokines – in addition to fatty acids and
other lipid moieties. A paradigm shift came with the discovery of leptin, a pleiotropic ... Cited by 156 - Related articles - BL Direct - All 7 versions
P Trayhurn, I Wood - Biochemical Society Transactions, 2005 - bst.portlandpress.com White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a wide
range of protein signals and factors termed adipokines. A number of adipokines, including
leptin, adiponectin, tumour necrosis factor a, IL-1b (interleukin 1b), IL-6, monocyte ... Cited by 144 - Related articles - Cached - BL Direct - All 10 versions
UN Das - Current Hypertension Reports, 2004 - Springer Introduction The incidence of metabolic syndrome X that is character- ized by abdominal
obesity, atherosclerosis, insulin resis- tance and hyperinsulinemia, hyperlipidemia, essential
hypertension, type 2 diabetes mellitus, and coronary heart disease (CHD) is increasing in ... Cited by 142 - Related articles - BL Direct - All 7 versions
PA Tataranni, E Ortega - Diabetes, 2005 - Am Diabetes Assoc There is growing support for the hypothesis that obesity is an inflammatory condition leading
to chronic activation of the innate immune system, which ultimately causes progressive impairment
of glucose tolerance. Experimental studies in animals and evidence from prospective and ... Cited by 103 - Related articles - All 9 versions
- ►oxfordjournals.org ES Schernhammer, JH Kang, AT Chan, … - JNCI Journal of the …, 2004 - jnci.oxfordjournals.org Background: In vitro experiments and limited animal studies suggest that aspirin and nonsteroidal
anti-inflammatory drugs may inhibit pancreatic carcinogenesis. Because few studies have examined
the association between aspirin use and pancreatic cancer in humans and the results ... Cited by 92 - Related articles - BL Direct - All 8 versions
P Trayhurn - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Obesity is a multidisciplinary area, the 'biology' of which encompasses: (1) the fundamental mechanisms
of energy balance and its regulation; (2) the biological basis for the development of obesity;
(3) adipose tissue function; (4) the biological description of the obese state; (5) the ... Cited by 66 - Related articles - All 6 versions
- ►nutrition.org P Trayhurn, C Bing, IS Wood - Journal of Nutrition, 2006 - Am Soc Nutrition There has been a rapid rise in the incidence of obesity, primarily as a result of changes in lifestyle
(diet and activity levels). Obesity has provided considerable impetus for the investigation of the
fundamental mechanisms involved in the regulation of energy balance. Important ... Cited by 55 - Related articles - All 5 versions
