- ►diabetesjournals.org JL Gross, MJ de Azevedo, SP Silveiro, LH Canani, … - Diabetes Care, 2005 - Am Diabetes Assoc Diabetic nephropathy is the leading cause of kidney disease in patients starting renal replacement
therapy and affects ∼40% of type 1 and type 2 diabetic patients. It increases the risk of
death, mainly from cardiovascular causes, and is defined by increased urinary albumin ... Cited by 218 - Related articles - All 18 versions
- ►nih.gov [PDF] PJ Thornalley, S Battah, N Ahmed, N … - Biochemical …, 2003 - pubmedcentral.nih.gov Glycation of proteins forms fructosamines and advanced gly- cation endproducts. Glycation adducts
may be risk markers and risk factors of disease development. We measured the concen- trations
of the early glycation adduct fructosyl-lysine and 12 advanced glycation endproducts by ... Cited by 155 - Related articles - BL Direct - All 7 versions
- ►oxfordjournals.org R Ramasamy, SJ Vannucci, SSD Yan, K Herold, SF … - Glycobiology, 2005 - Soc Glycobiology The products of nonenzymatic glycation and oxidation of proteins and lipids, the advanced glycation
end products (AGEs), accumulate in a wide variety of environments. AGEs may be generated
rapidly or over long times stimulated by a range of distinct triggering mechanisms, thereby ... Cited by 130 - Related articles - All 8 versions
S Yamagishi, T Imaizumi - Current pharmaceutical design, 2005 - ingentaconnect.com Abstract: Diabetic vascular complication is a leading cause of end-stage renal failure, acquired
blindness, a variety of neuropathies and accelerated atherosclerosis, which could account for
disabilities and high mortality rates in patients with diabetes. Recent large prospective ... Cited by 123 - Related articles - All 3 versions
I Dalle-Donne, G Aldini, M Carini, R … - Journal of Cellular …, 2006 - interscience.wiley.com Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein
function, which is considered a widespread indicator of severe oxidative damage and
disease-derived protein dysfunction. Whereas moderately carbonylated proteins are ... Cited by 87 - Related articles - BL Direct - All 3 versions
AL Perraud, CL Takanishi, B Shen, S Kang, MK … - Journal of Biological …, 2005 - ASBMB TRPM2 is a member of the transient receptor potential melastatin-related (TRPM) family of cation
channels, which possesses both ion channel and ADP-ribose hydrolase functions. TRPM2 has
been shown to gate in response to oxidative and nitrosative stresses, but the mechanism ... Cited by 79 - Related articles - All 6 versions
- ►critcaremed.org N Ahmed, PJ Thornalley - Diabetes, Obesity & Metabolism, 2007 - pt.wkhealth.com Glycation is a major cause of spontaneous damage to proteins in physiological systems. This
is exacerbated in diabetes as a consequence of the increase in glucose and other saccharides
derivatives in plasma and at the sites of vascular complications. Protein damage by the ... Cited by 64 - Related articles - All 7 versions
N Karachalias, R Babaei-Jadidi, N Ahmed … - Biochemical Society …, 2003 - bst.portlandpress.com The accumulation of AGEs (advanced glycation end products) in diabetes mellitus has been
implicated in the biochemical dysfunction associated with the chronic development of microvascular
complications of diabetes – nephropathy, retinopathy and peripheral neuropathy. We ... Cited by 62 - Related articles - Cached - BL Direct - All 8 versions
