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Scholar Results 1 - 10 of about 35 citing Wilson: Microarray analysis of gene expression in the kidneys of new-and post-onset diabetic.... (0.13 sec) 

Mouse models of diabetic nephropathy

- asnjournals.org
MD Breyer, E Bottinger, FC Brosius III, TM … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol
Mice provide an experimental model of unparalleled flexibility for studying
mammalian diseases. Inbred strains of mice exhibit substantial differences in
their susceptibility to the renal complications of diabetes. Much remains ...
Cited by 104 - Related articles - All 6 versions

Systematic changes in gene expression in postmortem human brains associated with tissue …

- oxfordjournals.org
JZ Li, MP Vawter, DM Walsh, H Tomita, SJ … - Human Molecular Genetics, 2004 - Oxford Univ Press
Studies of gene expression abnormalities in psychiatric or neurological
disorders often involve the use of postmortem brain tissue. Compared with
single-cell organisms or clonal cell lines, the biological environment and ...
Cited by 101 - Related articles - BL Direct - All 5 versions

Molecular profiling of diabetic mouse kidney reveals novel genes linked to glomerular …

- daegu.ac.kr [PDF] 
K Susztak, E Böttinger, A Novetsky, D Liang … - Diabetes, 2004 - Am Diabetes Assoc
To describe gene expression changes that characterize the development of
diabetic nephropathy, we performed microarray and phenotype analysis on kidneys
from db/db mice (a model of type 2 diabetes), streptozotocin-induced ...
Cited by 58 - Related articles - BL Direct - All 5 versions

Large-scale identification of genes implicated in kidney glomerulus development and …


M Takemoto, L He, J Norlin, J Patrakka, Z … - The EMBO Journal, 2006 - pubmedcentral.nih.gov
To advance our understanding of development, function and diseases in the kidney
glomerulus, we have established and large-scale sequenced cDNA libraries from
mouse glomeruli at different stages of development, resulting in a ...
Cited by 34 - Related articles - BL Direct - All 6 versions

Obesity-related glomerulopathy: insights from gene expression profiles of the glomeruli …

- endojournals.org
Y Wu, Z Liu, Z Xiang, C Zeng, Z Chen, X Ma, L … - Endocrinology, 2006 - Endocrine Soc
Obesity-related glomerulopathy (ORG) is an important complication of obesity.
The pathophysiological mechanism of glomerular injury in ORG is incompletely
understood. Gene expression profiles in the glomeruli obtained from renal ...
Cited by 35 - Related articles - BL Direct - All 6 versions

Diabetic nephropathy: a frontier for personalized medicine

- asnjournals.org
K Susztak, EP Bottinger - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Diabetic nephropathy (DNP) develops after latency periods that may vary by
several years in approximately one third of patients with diabetes. This
diabetic complication is a complex disorder whereby various genetic and ...
Cited by 30 - Related articles - BL Direct - All 5 versions

Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes

- physiology.org
KE Knoll, JL Pietrusz, M Liang - Physiological Genomics, 2005 - Am Physiological Soc
The understanding of common and tissue-specific molecular alterations in
diabetes, particularly at early stages, is limited and fragmental. In the
present study, we systematically compared transcriptome responses in four ...
Cited by 29 - Related articles - All 5 versions

Use of genetic mouse models in the study of diabetic nephropathy


TJ Allen, ME Cooper, HY Lan - Current Atherosclerosis Reports, 2004 - Springer
Introduction A large proportion of the knowledge on the pathophysiol- ogy of
diabetic nephropathy has come from studies performed in animal models of
diabetes. Indeed, impor- tant therapeutic strategies for diabetic ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Analysis of gene expression in pathophysiological states: balancing false discovery and …

- pnas.org
AW Norris, CR Kahn - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Nucleotide-microarray technology, which allows the simultaneous measurement of
the expression of tens of thousands of genes, has become an important tool in
the study of disease. In disorders such as malignancy, gene expression ...
Cited by 24 - Related articles - BL Direct - All 10 versions

A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in …


A Davoodi-Semiromi, M Laloraya, GP Kumar, S … - Journal of Biological Chemistry, 2004 - ASBMB
A number of cytokines that finely regulate immune response have been implicated
in the pathogenesis or protection of type 1 diabetes and other autoimmune
diseases. It is, therefore, of pivotal importance to examine a family of ...
Cited by 21 - Related articles - BL Direct - All 4 versions


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