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Scholar Results 1 - 10 of about 22 citing Kim: Genetic Modifiers of the Age at Diagnosis of Diabetes (MODY3) in Carriers of Hepatocyte.... (0.98 sec) 

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J …

- pubget.com [PDF] 
AA Toye, JD Lippiat, P Proks, K Shimomura, L … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 675–686 DOI 10.1007/s00125-005-1680-z ARTICLE AA
Toye . JD Lippiat . P. Proks . K. Shimomura . L.Bentley . A. Hugill . ...
Cited by 57 - Related articles - All 4 versions

Evidence from a large UK family collection that genes influencing age of onset of type …

- diabetesjournals.org
S Wiltshire, TM Frayling, CJ Groves, JC Levy … - Diabetes, 2004 - Am Diabetes Assoc
Additional information on genetic susceptibility effects relevant to type 2
diabetes pathogenesis can be extracted from existing genome scans by extending
examination to related phenotypes such as age at disease onset. In this ...
Cited by 26 - Related articles - BL Direct - All 5 versions

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in …

- gemstudy.ca [PDF] 
Y Yu, DF Wyszynski, DM Waterworth, SD … - Science's STKE, 2005 - stke.sciencemag.org
Abstract: We conducted a genome-wide scan using variance components linkage
analysis to localize quantitative-trait loci (QTLs) influencing triglyceride
(TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein- ...
Cited by 23 - Related articles - BL Direct - All 7 versions

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes


RJ Chaparro, Y Konigshofer, GF Beilhack, JA … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Before the onset of autoimmune destruction, type 1 diabetic patients and an
animal model, the nonobese diabetic (NOD) mouse, show morphological and
functional abnormalities in target organs, which may act as inciting events ...
Cited by 21 - Related articles - BL Direct - All 10 versions

Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential …

- oxfordjournals.org
LW Harries, S Ellard, A Stride… - Human Molecular Genetics, 2006 - Oxford Univ Press
The generation of multiple transcripts by mRNA processing has the potential to
moderate differences in gene expression both between tissues and at different
stages of development. Where gene function is compromised by mutation, the ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Identification of human aminopeptidase O, a novel metalloprotease with structural …

- jbc.org
A Diaz-Perales, V Quesada, LM Sanchez, AP … - Journal of Biological Chemistry, 2005 - ASBMB
We have cloned and characterized a human brain cDNA encoding a new
metalloprotease that has been called aminopeptidase O (AP-O). AP-O exhibits a
series of structural features characteristic of aminopeptidases, including ...
Cited by 14 - Related articles - All 6 versions

The type and the position of HNF1A mutation modulate age at diagnosis of diabetes in …


C Bellanné-Chantelot, C Carette, JP Riveline … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Missense mutations prevailed in the dimerization and DNA-binding
domains (74%), while truncating mutations were predominant in the
transactivation domain (62%). The majority (83%) of the mutations were ...
Cited by 15 - Related articles - BL Direct - All 4 versions

High-resolution physical mapping and construction of a porcine contig spanning the …


S Sato, H Hasebe, S Sato, Y Asahi, T Hayashi … - Animal Genetics, 2006 - interscience.wiley.com
We previously mapped a locus for porcine intramuscular fat content (IMF) by
linkage analysis to a 17.1-cM chromosome interval on Sus scrofa chromosome 7
(SSC7) flanked by microsatellite markers SW1083 and SW581. In this study, ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Preliminary evidence of genetic anticipation in type 2 diabetes mellitus.


S Yaturu, JF Bridges, RR Dhanireddy - Medical science monitor: international medical journal …, 2005 - ncbi.nlm.nih.gov
BACKGROUND: The term "anticipation" in genetic diseases refers to earlier age at
onset and/or increased severity in successive generations. Several diseases with
genetic anticipation include rheumatoid arthritis, Crohn's disease, ...
Cited by 5 - Related articles - All 5 versions


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