- ►jbc.org RL Hurley, KA Anderson, JM Franzone, BE … - Journal of Biological Chemistry, 2005 - ASBMB The AMP-activated protein kinase (AMPK) is an important regulator of cellular
metabolism in response to metabolic stress and to other regulatory signals. AMPK
activity is absolutely dependent upon phosphorylation of AMPK Thr-172 in ... Cited by 274 - Related articles - BL Direct - All 6 versions
- ►physiology.org K Sakamoto, O Goransson, DG Hardie, DR … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Activation of AMP-activated protein kinase (AMPK) by exercise and metformin is
beneficial for the treatment of type 2 diabetes. We recently found that, in
cultured cells, the LKB1 tumor suppressor protein kinase activates AMPK in ... Cited by 118 - Related articles - BL Direct - All 4 versions
- ►nih.gov HC Dreyer, S Fujita, JG Cadenas, DL … - The Journal of Physiology, 2006 - Physiological Soc Resistance exercise is a potent stimulator of muscle protein synthesis and
muscle cell growth, with the increase in protein synthesis being detected within
2–3 h post-exercise and remaining elevated for up to 48 h. However, ... Cited by 83 - Related articles - BL Direct - All 8 versions
- ►nih.gov VA Narkar, M Downes, RT Yu, E Embler, YX … - Cell, 2008 - Elsevier The benefits of endurance exercise on general health make it desirable to
identify orally active agents that would mimic or potentiate the effects of
exercise to treat metabolic diseases. Although certain natural compounds, ... Cited by 72 - Related articles - All 12 versions
- ►physiology.org K Sakamoto, E Zarrinpashneh, GR Budas, AC … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Recent studies indicate that the LKB1 is a key regulator of the AMP-activated
protein kinase (AMPK), which plays a crucial role in protecting cardiac muscle
from damage during ischemia. We have employed mice that lack LKB1 in ... Cited by 72 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org SL McGee, M Hargreaves - Diabetes, 2004 - Am Diabetes Assoc Overexpression of GLUT4 in skeletal muscle enhances whole-body insulin action.
Exercise increases GLUT4 gene and protein expression, and a binding site for the
myocyte enhancer factor 2 (MEF-2) is required on the GLUT4 promoter for ... Cited by 68 - Related articles - BL Direct - All 4 versions
JY Altarejos, M Taniguchi, AS Clanachan, … - Journal of Biological Chemistry, 2005 - ASBMB During myocardial ischemia, activation of 5'-AMP-activated protein kinase (AMPK)
leads to the stimulation of glycolysis and fatty acid oxidation. Together these
metabolic changes contribute to cardiac dysfunction. Although AMPK ... Cited by 65 - Related articles - All 7 versions
- ►physiology.org AJ Rose, EA Richter - Physiology, 2005 - Am Physiological Soc During dynamic exercise, the turnover of ATP in skeletal muscle increases
greatly and is fuelled by the catabolism of carbohydrates (intramuscular
glycogen, blood glucose) and fatty acids (intramuscular triglycerides, ... Cited by 60 - Related articles - BL Direct - All 4 versions
- ►nih.gov JB Birk, JFP Wojtaszewski - The Journal of physiology, 2006 - Physiological Soc 5′AMP-activated protein kinase (AMPK) is a key regulator of cellular
metabolism and is regulated in muscle during exercise. We have previously
established that only three of 12 possible AMPK α/β/γ-heterotrimers are ... Cited by 51 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org A Sriwijitkamol, DK Coletta, E Wajcberg, GB … - Diabetes, 2007 - Am Diabetes Assoc Activation of AMP-activated protein kinase (AMPK) by exercise induces several
cellular processes in muscle. Exercise activation of AMPK is unaffected in lean
(BMI ∼25 kg/m 2 ) subjects with type 2 diabetes. However, most type 2 ... Cited by 51 - Related articles - BL Direct - All 4 versions
