- ►mdc-berlin.de [PDF] O Aktas, A Smorodchenko, S Brocke, C Infante-Duarte, … - Neuron, 2005 - Elsevier Here, we provide evidence for a detrimental role of tumor necrosis factor-related apoptosis-inducing
ligand (TRAIL) in neural death in T cell-induced experimental autoimmune encephalomyelitis
(EAE), an animal model of multiple sclerosis (MS). Clinical severity and neuronal ... Cited by 78 - Related articles - All 6 versions
E Cretney, A Shanker, H Yagita, MJ Smyth, TJ … - Immunology and cell …, 2006 - nature.com Recombinant, soluble TNF-related apoptosis-inducing ligand (TRAIL) is currently being developed
as a promising natural immune molecule for trial in cancer patients because it selectively induces
apoptosis in transformed or stressed cells but not in most normal cells. In cancer patients, ... Cited by 53 - Related articles - BL Direct - All 5 versions
LA Ryan, H Peng, DA Erichsen, Y Huang, Y … - Journal of …, 2004 - Elsevier TNF-related apoptosis-inducing ligand (TRAIL) is a type II integral membrane protein that interacts
with multiple receptors and cell types including neurons. In this report, TRAIL protein levels were
increased in human monocyte-derived macrophages (MDM) after HIV-1 infection and ... Cited by 35 - Related articles - All 8 versions
U Schaefer, O Voloshanenko, D Willen, H Walczak - Front Biosci, 2007 - bioscience.org The Tumor necrosis factor (TNF)-Related Apoptosis Inducing Ligand, TRAIL, has gained much
attention due to its specific anti-tumor potential without toxic side effects. TRAIL binds to a complex
receptor system. In humans there are two death-inducing receptors for TRAIL while only ... Cited by 34 - Related articles - View as HTML - All 2 versions
- ►jimmunol.org SJ Zheng, J Jiang, H Shen, YH Chen - The Journal of Immunology, 2004 - Am Assoc Immnol Listeriosis is an infectious disease caused by the bacterium Listeria monocytogenes. Although
it is well recognized that apoptosis plays a critical role in the pathogenesis of the disease, the
molecular mechanisms of cell death in listeriosis remain to be established. We report in ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org JJ Lum, G Bren, R McClure, AD Badley - The Journal of Immunology, 2005 - Am Assoc Immnol Neutrophils are phagocytic effectors which are produced in the bone marrow and released into
the circulation. Thereafter, they are either recruited to sites of inflammation or rapidly become
senescent, return to the bone marrow, and undergo apoptosis. Stromal cell-derived factor ... Cited by 25 - Related articles - BL Direct - All 7 versions
E Cretney, JL McQualter, N Kayagaki, H Yagita, … - Immunology and cell …, 2005 - nature.com Studies have suggested that endogenous TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L
may suppress the induction of some autoimmune diseases in mice. Here, we show that
TRAIL/Apo2L suppresses autoimmune damage in relapsing-remitting, and non-remitting ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►nih.gov N Finnberg, AJP Klein-Szanto, WS El- … - Journal of Clinical …, 2007 - Am Soc Clin Investig Preclinical data support the potential of the death-signaling receptors for TRAIL as targets for
cancer therapy. However, it is unclear whether these death-signaling receptors suppress the
emergence and growth of malignant tumors in vivo. Herein we show that TNF-related ... Cited by 21 - Related articles - BL Direct - All 7 versions
EPK Mensah-Brown, A Shahin, M Al- … - European journal of …, 2006 - interscience.wiley.com IL-23, a proximal regulator of IL-17, may be a major driving force in the induction of autoimmune
inflammation. We have used a model of subdiabetogenic treatment with multiple low doses of
streptozotocin (MLD-STZ; 4 × 40 mg/kg body weight) in male C57BL/6 mice to study the ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org C Lorz, A Benito-Martin, A Boucherot, AC … - Journal of the American …, 2008 - Am Soc Nephrol Apoptotic cell death contributes to diabetic nephropathy (DN), but its role is not well
understood. The tubulointerstitium from DN biopsy specimens was microdissected, and expression
profiles of genes related to apoptosis were analyzed. A total of 112 (25%) of 455 cell ... Cited by 18 - Related articles - All 5 versions
