- ►daegu.ac.kr [PDF] R Sladek, G Rocheleau, J Rung, C Dina, L … - Nature, 2007 - nature.com Type 2 diabetes mellitus results from the interaction of environmental factors
with a combination of genetic variants, most of which were hitherto unknown. A
systematic search for these variants was recently made possible by the ... Cited by 770 - Related articles - BL Direct - All 14 versions
- ►endojournals.org RL Hull, GT Westermark, P Westermark, SE … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Islet amyloid deposition is a pathogenic feature of type 2 diabetes, and these
deposits contain the unique amyloidogenic peptide islet amyloid polypeptide.
Autopsy studies in humans have demonstrated that islet amyloid is ... Cited by 119 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] N Grarup, CS Rose, EA Andersson, G Andersen … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2
Genes With Type 2 Diabetes and Impaired Insulin Release ... Cited by 58 - Related articles - BL Direct - All 3 versions
MR Nicolls - Current Alzheimer Research, 2004 - ingentaconnect.com Abstract: The clinical relationship between Type II diabetes mellitus and
Alzheimer's disease has been debated for over a decade. While several studies
have not shown a clear clinical correlation, others have demonstrated that ... Cited by 31 - Related articles - All 5 versions
- ►cell.com Q Li, MA Ali, JI Cohen - Cell, 2006 - Elsevier Varicella-zoster virus (VZV) causes chickenpox and shingles. While varicella is
likely spread as cell-free virus to susceptible hosts, the virus is transmitted
by cell-to-cell spread in the body and in vitro. Since VZV glycoprotein E ... Cited by 32 - Related articles - All 10 versions
- ►endojournals.org L Haataja, T Gurlo, CJ Huang, PC Butler - Endocrine Reviews, 2008 - Endocrine Soc Type 2 diabetes (T2DM) is characterized by insulin resistance, defective insulin
secretion, loss of β-cell mass with increased β-cell apoptosis and islet
amyloid. The islet amyloid is derived from islet amyloid polypeptide (IAPP, ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►jbc.org H Im, M Manolopoulou, E Malito, Y Shen, J … - Journal of Biological Chemistry, 2007 - ASBMB Insulin-degrading enzyme (IDE) is a zinc metalloprotease that hydrolyzes
amyloid- (A ) and insulin, which are peptides associated with Alzheimer disease
(AD) and diabetes, respectively. Our previous structural analysis of ... Cited by 20 - Related articles - All 5 versions
SFA Grant, H Hakonarson - Expert Rev. Mol. Diagn., 2007 - mp.medscape.com Genetic diversity, most notably through single nucleotide polymorphisms and
copy-number variation, together with specific environmental exposures,
contributes to both disease susceptibility and drug response variability. ... Cited by 16 - Related articles - BL Direct - All 10 versions
MK Sun, DL Alkon - Drugs of Today, 2006 - journals.prous.com The existence of links between Alzheimer's disease and diabetes is an important
topic currently under active debate. Establishing such links if they exist and
defining their common pathogenesis and pathophysiological mechanisms may ... Cited by 16 - Related articles - All 6 versions
