- ►endojournals.org B Desvergne, L Michalik, W Wahli - Molecular Endocrinology, 2004 - Endocrine Soc Investigating metabolism by unveiling the functions of the nuclear receptors
peroxisome proliferator-activated receptors (PPARs) in the numerous intricate
pathways ensuring energy homeostasis and fitness has been extremely ... Cited by 129 - Related articles - BL Direct - All 8 versions
- ►nih.gov D Patsouris, S Mandard, PJ Voshol, P Escher, … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig 1 Nutrition, Metabolism and Genomics Group, Division of Human Nutrition,
Wageningen University, Wageningen, The Netherlands. 2 Department of
Endocrinology and Diabetes, Leiden University Medical Center, Leiden, The ... Cited by 92 - Related articles - BL Direct - All 8 versions
KC Choi, OH Ryu, KW Lee, HY Kim, JA Seo, … - Biochemical and biophysical research communications, 2005 - Elsevier A variety of adipocytokines and peptides secreted from adipocytes have been
considered to play a crucial role in obesity, insulin resistance, and type 2
diabetes. Recently, visfatin, a new adipocytokine, known as a pre-B cell ... Cited by 94 - Related articles - All 4 versions
- ►asnjournals.org Y Guan - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol Peroxisome proliferator-activated receptors (PPAR) are members of the nuclear
hormone receptor superfamily of ligand-activated transcription factors. Three
PPAR isoforms, designated PPAR , - / , and - , have been identified and ... Cited by 89 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org MJ Watt, RJ Southgate, AG Holmes, MA … - Journal of molecular endocrinology, 2004 - Soc Endocrinology Fatty acids are an important ligand for peroxisome proliferator-activated
receptor (PPAR) activation and transcriptional regulation of metabolic genes. To
examine whether reduced plasma free fatty acid (FFA) availability affects ... Cited by 55 - Related articles - BL Direct - All 4 versions
- ►endojournals.org K Ravnskjaer, M Boergesen, B Rubi, JK Larsen … - Endocrinology, 2005 - Endocrine Soc Fatty acids (FAs) are known to be important regulators of insulin secretion from
pancreatic ß-cells. FA-coenzyme A esters have been shown to directly stimulate
the secretion process, whereas long-term exposure of ß-cells to FAs ... Cited by 44 - Related articles - BL Direct - All 2 versions
- ►shouxi.net DM Flavell, H Ireland, JW Stephens, E Hawe, … - Diabetes, 2005 - Am Diabetes Assoc Dysregulation of fatty acid metabolism is important in the pathogenesis of type
2 diabetes. Peroxisome proliferator-activated receptor (PPAR)α is a master
regulator of fatty acid catabolism, and PPARα activators delay the onset ... Cited by 41 - Related articles - All 7 versions
CW Park, Y Zhang, X Zhang, J Wu, L Chen, DR … - Kidney International, 2006 - nature.com Peroxisome proliferator-activated receptor (PPAR ) is a member of the
ligand-activated nuclear receptor superfamily, and plays an important role in
lipid metabolism and glucose homeostasis. The purpose of this study is to ... Cited by 39 - Related articles - BL Direct - All 3 versions
B Pourcet, JC Fruchart, B Staels, C Glineur - Expert Opin. Emerging Drugs, 2006 - informahealthcare.com More than 70% of patients with Type 2 diabetes mellitus (T2DM) die because of
cardiovascular diseases. Current therapeutic strategies are based on separate
treatment of insulin resistance and dyslipidaemia. Development of drugs ... Cited by 40 - Related articles - BL Direct - All 6 versions
