- ►ahajournals.org A Ceriello, E Motz - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc Type 2 diabetes is a worldwide increasing disease resulting from the interaction between a subject's
genetic makeup and lifestyle. In genetically predisposed subjects, the combination of excess
caloric intake and reduced physical activity induces a state of insulin resistance. When ... Cited by 388 - Related articles - BL Direct - All 9 versions
JL Evans, BA Maddux, ID Goldfine - Antioxidants & Redox Signaling, 2005 - liebertonline.com O XIDATIVE STRESS , defined as a persistent imbalance be- tween the production of highly
reactive molecular species (chiefly oxygen and nitrogen; Table 1) and antioxi- dant defenses
(Fig. 1), is associated with a wide variety of pa- thologies, including diabetes, ... Cited by 73 - Related articles - BL Direct - All 4 versions
JA Hawley - Diabetes/Metabolism Reviews - interscience.wiley.com During the past half-century, there has been a dramatic increase in the incidence of obesity,
insulin resistance and type 2 diabetes. A hallmark feature of these conditions is impaired glucose
tolerance (IGT). Cross-sectional and retrospective epidemiological studies have provided ... Cited by 63 - Related articles - BL Direct - All 4 versions
S Quan, PM Kaminski, L Yang, T Morita, M Inaba, S … - … and Biophysical Research …, 2004 - Elsevier Heme oxygenase-1 (HO-1) represents a key defense mechanism against oxidative injury. Hyperglycemia
has been linked to increased oxidative stress, leading to endothelial dysfunction, delayed cell
replication, and enhanced apoptosis. The effect of streptozotocin (STZ)-induced diabetes ... Cited by 48 - Related articles - All 4 versions
H Sell, D Dietze-Schroeder, J Eckel - Trends in Endocrinology & Metabolism, 2006 - Elsevier Insulin resistance in skeletal muscle is linked to an elevated adipose tissue mass, as is found
in obesity, but can also be observed in lipodystrophy, in which adipose tissue is greatly
reduced. Adipose tissue releases endocrine and metabolic mediators and is actively ... Cited by 48 - Related articles - All 3 versions
CH Tseng - Toxicology and applied pharmacology, 2004 - Elsevier Although epidemiologic studies carried out in Taiwan, Bangladesh, and Sweden have demonstrated
a diabetogenic effect of arsenic, the mechanisms remain unclear and require further
investigation. This paper reviewed the potential biological mechanisms of ... Cited by 45 - Related articles - All 9 versions
LE Fridlyand, LH Philipson - Diabetes Obesity and Metabolism, 2006 - interscience.wiley.com The early stages of type 2 diabetes mellitus are characterized by the development of insulin resistance
(IRe) in muscle cells and adipocytes with the concomitant loss of β-cell compensation. We have
extensively reviewed the literature related to metabolic and signalling pathways of ... Cited by 45 - Related articles - BL Direct - All 4 versions
- ►jacn.org Y Song, JAE Manson, JE Buring, HD Sesso, … - Journal of the American …, 2005 - Am Coll Nutrition Results: During 332,905 person-years of follow-up, none of total flavonols and flavones,
quercetin, kaempferol, myricetin, apigenin, and luteolin was significantly associated with risk
of type 2 diabetes. Among flavonoid-rich foods, apple and tea consumption was ... Cited by 39 - Related articles - BL Direct - All 7 versions
- ►pubget.com [PDF] JA McClung, N Naseer, M Saleem, GP Rossi, MB … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Patients with diabetes melli- tus are well known to be at high risk for
vascular disease. Circulating endothelial cells (CECs) have been reported to be an ex vivo indicator
of vascular injury. We inves- tigated the presence of CECs in the peripheral blood of 25 ... Cited by 39 - Related articles - All 4 versions
CR BRUCE, JA HAWLEY - Medicine & Science in Sports & Exercise, 2004 - journals.lww.com BRUCE, CR, and JA HAWLEY. Improvements in Insulin Resistance with Aerobic Exercise
Training: A Lipocentric Approach. Med. Sci. Sports Exerc., Vol. 36, No. 7, pp. 1196-1201,
2004. Traditional views on the metabolic derangements underlying insulin resistance and ... Cited by 37 - Related articles - BL Direct - All 3 versions
