P Pacher, IG Obrosova, JG Mabley, C Szabó - Current medicinal chemistry, 2005 - pubmedcentral.nih.gov Macro- and microvascular disease are the most common causes of morbidity and
mortality in patients with diabetes mellitus. Diabetic cardiovascular
dysfunction represents a problem of great clinical importance underlying ... Cited by 80 - Related articles - All 9 versions
AM Vincent, JA Olzmann, M Brownlee, WI … - Diabetes, 2004 - Am Diabetes Assoc The central role of mitochondria in most pathways leading to programmed cell
death (PCD) has focused our investigations into the mechanisms of
glucose-induced neuronal degeneration. It has been postulated that ... Cited by 72 - Related articles - BL Direct - All 4 versions
GM Leinninger, AM Vincent, EL Feldman - Journal of the peripheral nervous system, 2004 - etc.leinninger.com Abstract Peripheral neuropathy afflicts 60% of all diabetic patients. Underlying
the clinical disorder is the loss or degeneration of neurons, Schwann cells, and
neuronal fibers. This degenerative pathology has prompted interest in the ... Cited by 55 - Related articles - View as HTML - BL Direct - All 4 versions
DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer The morbidity and mortality associated with diabetes is the result of the myriad
complications related to the disease. One of the most explored hypotheses to
explain the onset of complications is a hyperglycemia-induced increase in ... Cited by 52 - Related articles - BL Direct - All 6 versions
AAF Sima - eid, 2003 - informahealthcare.com 1. Introduction 2. The natural history of diabetic polyneuropathy in Type 1 and
Type 2 diabetes 3. Pathogenetic considerations in Type 1 and Type 2 diabetic
polyneuropathy 4. The effect of C-peptide on experimental Type 1 diabetic ... Cited by 45 - Related articles - All 4 versions
R Pop-Busui, A Sima, M Stevens - Diabetes/Metabolism Reviews - interscience.wiley.com This review will focus on the impact of hyperglycemia-induced oxidative stress
in the development of diabetes-related neural dysfunction. Oxidative stress
occurs when the balance between the production of reactive oxygen species ... Cited by 42 - Related articles - BL Direct - All 3 versions
- ►inotekcorp.com [PDF] F Li, C Szabo, P Pacher, GJ Southan, OI … - Diabetologia, 2004 - Springer Aims/hypothesis. Poly(ADP-ribose) polymerase acti- vation depletes NAD + and
high-energy phosphates, activates protein kinase C, and affects gene expression
in various tissues. This study was designed to charac- terise the effects ... Cited by 38 - Related articles - BL Direct - All 11 versions
- ►nih.gov P Pacher, C Szabó - Antioxidants & redox signaling, 2005 - liebertonline.com Hyperglycemia-induced overproduction of superoxide by mitochondrial
electron-transport chain triggers several pathways of injury involved in the
pathogenesis of diabetic complications [protein kinase C (PKC), hexosamine ... Cited by 38 - Related articles - BL Direct - All 6 versions
IG Obrosova, AG Minchenko, RN Frank, GM … - International journal of molecular medicine, 2004 - inotekcorp.com INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 14: 55-64, 2004 Poly(ADP-ribose)
polymerase inhibitors counteract diabetes» and hypoxia-induced retinal vascular
endothelial growth factor overexpression IRINA G. OBROSOVA1, ALEXANDER G. ... Cited by 38 - Related articles - BL Direct - All 7 versions
