- ►nih.gov MG Hartman, D Lu, ML Kim, GJ Kociba, T … - Molecular and Cellular Biology, 2004 - Am Soc Microbiol Activating transcription factor 3 (ATF3) is a stress-inducible gene and encodes
a member of the ATF/CREB family of transcription factors. However, the
physiological significance of ATF3 induction by stress signals is not ... Cited by 85 - Related articles - BL Direct - All 11 versions
- ►jimmunol.org BJ O'Sullivan, HE Thomas, S Pai, P … - The Journal of Immunology, 2006 - Am Assoc Immnol IL-1 is a key proinflammatory driver of several autoimmune diseases including
juvenile inflammatory arthritis, diseases with mutations in the NALP/cryopyrin
complex and Crohn's disease, and is genetically or clinically associated ... Cited by 44 - Related articles - BL Direct - All 3 versions
- ►pasteur.ac.ir [PDF] N Yuki - Current opinion in immunology, 2005 - Elsevier Molecular mimicry of microbial components by self components is thought to be
the mechanism that accounts for the antigen and tissue specificity of immune
responses in post-infectious autoimmune diseases. Little direct evidence ... Cited by 38 - Related articles - All 6 versions
- ►pnas.org S Kim, I Millet, HS Kim, JY Kim, MS Han, MK … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Whereas NF-κB has potent antiapoptotic function in most cell types, it was
reported that in pancreatic β cells it serves a proapoptotic function and may
contribute to the pathogenesis of autoimmune type 1 diabetes. To ... Cited by 31 - Related articles - BL Direct - All 10 versions
RA Mahmoud, SA el-Ezz, AS Hegazy - The Italian journal of biochemistry, 2004 - ncbi.nlm.nih.gov In the present study we measured interleukin-18 (IL-18) and tumour necrosis
factor-alpha (TNF-alpha) levels by enzyme linked immunosorbent assay (ELISA) in
sera from 65 diabetic [30 with type 1 insulin dependent diabetes mellitus ... Cited by 26 - Related articles - All 2 versions
- ►jimmunol.org J Allison, HE Thomas, T Catterall, TWH Kay, A … - The Journal of Immunology, 2005 - Am Assoc Immnol In type 1 diabetes, many effector mechanisms damage the cell, a key one being
perforin/granzyme B production by CD8 + T cells. The death receptor pathway has
also been implicated in cell death, and we have therefore generated NOD ... Cited by 26 - Related articles - All 7 versions
J He, I Usui, K Ishizuka, Y Kanatani, K … - Molecular Endocrinology, 2006 - Endocrine Soc Proinflammatory cytokines are recently reported to inhibit insulin signaling
causing insulin resistance. IL-1 is also one of the proinflammatory cytokines;
however, it has not been clarified whether IL-1 may also cause insulin ... Cited by 25 - Related articles - BL Direct - All 3 versions
U Walter, P Santamaria - Current opinion in immunology, 2005 - Elsevier Mounting evidence shows that CD8 + T cells contribute to the initiation,
progression and regulation of several pathogenic autoimmune responses in which
these cells were not previously thought to play a major role. CD8 + T cells ... Cited by 23 - Related articles - All 3 versions
- ►endojournals.org MY Donath, J Storling, LA Berchtold, N … - Endocrine Reviews, 2008 - Endocrine Soc The tale of cytokines and the β-cell is a long story, starting with in vitro
discovery in 1984, evolving via descriptive and phenomenological studies to
detailed mapping of the signalling pathways, gene- and protein expression ... Cited by 21 - Related articles - BL Direct - All 6 versions
NL Dudek, HE Thomas, L Mariana, RM … - Diabetes, 2006 - Am Diabetes Assoc Cytotoxic T-cells are the major mediators of β-cell destruction in type 1
diabetes, but the molecular mechanisms are not definitively established. We have
examined the contribution of perforin and Fas ligand to β-cell destruction ... Cited by 20 - Related articles - BL Direct - All 6 versions
