- ►endojournals.org RL Hull, GT Westermark, P Westermark, SE … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Islet amyloid deposition is a pathogenic feature of type 2 diabetes, and these
deposits contain the unique amyloidogenic peptide islet amyloid polypeptide.
Autopsy studies in humans have demonstrated that islet amyloid is ... Cited by 118 - Related articles - BL Direct - All 6 versions
MR Hayden, SC Tyagi, MM Kerklo, MR Nicolls - JOP. J Pancreas (Online), 2005 - joplink.net JOP. Journal of the Pancreas – http://www.joplink.net – Vol. 6, No. 4 –
July 2005. [ISSN 1590-8577] ... Type 2 Diabetes Mellitus as a Conformational
Disease ... Melvin R Hayden1, Suresh C Tyagi2, Michelle M Kerklo3, Mark R ... Cited by 43 - Related articles - View as HTML - All 5 versions
JF Paulsson, GT Westermark - Diabetes, 2005 - Am Diabetes Assoc The amyloid present in the islets of Langerhans in type 2 diabetes is
polymerized islet amyloid polypeptide (IAPP). The precursor protein proIAPP is
posttranslationally modified, a process involving the removal of NH 2 - and ... Cited by 25 - Related articles - All 5 versions
- ►shouxi.net L Marzban, CJ Rhodes, DF Steiner, L Haataja … - Diabetes, 2006 - Am Diabetes Assoc Islet amyloid, formed by aggregation of islet amyloid polypeptide (IAPP;
amylin), is a pathological characteristic of the pancreas in type 2 diabetes and
may contribute to the progressive loss of β-cells in this disease. We ... Cited by 18 - Related articles - BL Direct - All 5 versions
JF Paulsson, A Andersson, P Westermark, GT … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Islet amyloid is a frequent finding in the islets of
Langerhans of individuals with type 2 diabetes. The main amyloid constituent is
the beta cell- derived polypeptide hormone islet amyloid polypeptide ... Cited by 16 - Related articles - BL Direct - All 3 versions
- ►jbc.org R Ugleholdt, MLH Poulsen, PJ Holst, JC … - Journal of Biological Chemistry, 2006 - ASBMB The physiology of the incretin hormones, glucagon-like peptide 1 (GLP-1) and
glucose-dependent insulinotropic polypeptide (GIP), and their role in type 2
diabetes currently attract great interest. Recently we reported an ... Cited by 11 - Related articles - BL Direct - All 7 versions
L Marzban, G Soukhatcheva, CB Verchere - Endocrinology, 2005 - Endocrine Soc Islet amyloid polypeptide (IAPP; amylin) is a peptide hormone that is cosecreted
with insulin from ß-cells. Impaired processing of proIAPP, the IAPP precursor,
has been implicated in islet amyloid formation in type 2 diabetes. We ... Cited by 11 - Related articles - All 5 versions
- ►nih.gov IT Yonemoto, GJA Kroon, HJ Dyson, WE Balch … - Biochemistry, 2008 - pubs.acs.org Human amylin, or islet amyloid polypeptide, is a peptide cosecreted with insulin
by the beta cells of the pancreatic islets of Langerhans. The 37-residue,
C-terminally amidated human amylin peptide derives from a proprotein that ... Cited by 11 - Related articles - All 5 versions
GS Jeha, RA Heptulla - Pediatric Diabetes, 2006 - interscience.wiley.com Abstract: Recent studies in adult patients with type 1 diabetes mellitus (T1DM)
and T2DM have examined the potential utility, benefits, and side effects of
agents that augment insulin secretion after oral ingestion of nutrients in ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►endojournals.org L Marzban, G Trigo-Gonzalez, CB Verchere - Molecular Endocrinology, 2005 - Endocrine Soc Islet amyloid is a pathologic characteristic of the pancreas in type 2 diabetes
comprised mainly of the ß-cell peptide islet amyloid polypeptide (IAPP;
amylin). We used a pulse-chase approach to investigate the kinetics of ... Cited by 6 - Related articles - BL Direct - All 4 versions
