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Scholar Results 1 - 10 of about 51 citing Raza: Elevated mitochondrial cytochrome P450 2E1 and glutathione S-transferase A4-4 in streptozot.... (0.09 sec) 

The ins and outs of mitochondrial dysfunction in NASH

- alfediam.org [PDF] 
B Fromenty, MA Robin, A Igoudjil, A Mansouri … - Diabetes and Metabolism, 2004 - Elsevier
Rich diet and lack of exercise are causing a surge in obesity, insulin
resistance and steatosis, which can evolve into steatohepatitis. Steatosis and
nonalcoholic steatohepatitis (NASH) can also be induced by drugs such as ...
Cited by 104 - Related articles - BL Direct - All 4 versions

Mitochondrial injury in steatohepatitis


D Pessayre, B Fromenty, A Mansouri - European journal of gastroenterology & hepatology, 2004 - journals.lww.com
Rich diet and lack of exercise are causing a surge in obesity, insulin
resistance and steatosis, which can evolve into steatohepatitis. Patients with
non-alcoholic steatohepatitis have increased lipid peroxidation, increased ...
Cited by 63 - Related articles - BL Direct - All 3 versions

Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined …


K Otani, M Korenaga, MR Beard, K Li, T Qian … - Gastroenterology, 2005 - Elsevier
Background & Aims: Alcohol consumption exacerbates liver injury in chronic
hepatitis C, and enhanced mitochondrial oxidative stress is one possible
mechanism. The aim of this study was to determine whether hepatitis C virus ...
Cited by 38 - Related articles - All 14 versions

Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and …

- jbc.org
SK Prabu, HK Anandatheerthavarada, H Raza, … - Journal of Biological Chemistry, 2006 - ASBMB
We have investigated the effects of hypoxia and myocardial ischemia/reperfusion
on the structure and function of cytochrome c oxidase (CcO). Hypoxia (0.1% O 2
for 10 h) and cAMP-mediated inhibition of CcO activity were accompanied by ...
Cited by 32 - Related articles - BL Direct - All 7 versions

Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by …

- jbc.org
J Bai, AI Cederbaum - Journal of Biological Chemistry, 2006 - ASBMB
Induction of CYP2E1 by ethanol is one mechanism by which ethanol causes
oxidative stress and alcohol liver disease. Although CYP2E1 is predominantly
found in the endoplasmic reticulum, it is also located in rat hepatic ...
Cited by 26 - Related articles - BL Direct - All 5 versions

CYP2E1 and oxidative liver injury by alcohol

- nih.gov
Y Lu, AI Cederbaum - Free Radical Biology and Medicine, 2007 - Elsevier
Ethanol-induced oxidative stress seems to play a major role in mechanisms by
which ethanol causes liver injury. Many pathways have been suggested to
contribute to the ability of ethanol to induce a state of oxidative stress. ...
Cited by 25 - Related articles - All 5 versions

Effect of streptozotocin-induced diabetes on oxidative energy metabolism in rat kidney …


SS Katyare, JG Satav - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 16 - Related articles - BL Direct - All 4 versions

Differential susceptibility of naive and differentiated PC-12 cells to methylglyoxal-induced …

- bentham.org [PDF] 
M Okouchi, N Okayama, TY Aw - Current Neurovascular Research, 2005 - ingentaconnect.com
Abstract: Neuropathologies have been associated with neuronal de-differentiation
and oxidative susceptibility. To address whether cellular states determines
their oxidative vulnerability, we have challenged naive (undifferentiated) ...
Cited by 16 - Related articles - All 5 versions

Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: …


LE Fridlyand, LH Philipson - Current Diabetes Reviews, 2006 - ingentaconnect.com
Abstract: Insulin resistance (IRe) and a failure of insulin secretion are the
major features of the early pathophysiology of type-2 diabetes mellitus (T2D)
but the etiology is still not well understood. We suggest that: 1. The ...
Cited by 15 - Related articles - BL Direct - All 2 versions

Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats

- edulife.com.br [PDF] 
… YZ Maksimchik, SV Zabrodskaya, VL Kubyshin … - European journal of pharmacology, 2007 - Elsevier
Enhanced oxidative stress and impairments in nitric oxide synthesis and
bioavailability are of considerable importance in the pathogenesis of diabetic
vascular diseases. The aim of the present work was to evaluate the ...
Cited by 15 - Related articles - All 5 versions


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