EE Schadt, J Lamb, X Yang, J Zhu, S Edwards … - Rn - soph.uab.edu A key goal of biomedical research is to elucidate the complex network of gene
interactions underlying complex traits such as common human diseases. Here we
detail a multistep procedure for identifying potential key drivers of ... Cited by 225 - Related articles - All 14 versions
- ►ahajournals.org AJ Lusis, AM Fogelman, GC Fonarow - Circulation, 2004 - Am Heart Assoc Atherosclerosis, the primary cause of coronary heart disease (CHD), involves
numerous cell types and organs and a number of disparate physiological processes
(see Figure 1). 1–3 It is not surprising, then, that the genetic basis of ... Cited by 89 - Related articles - BL Direct - All 6 versions
GH Gibbons, CC Liew, MO Goodarzi, JI Rotter … - Circulation, 2004 - Am Heart Assoc From the Cardiovascular Research Institute (GHG), Morehouse School of Medicine,
Atlanta, Ga; the Department of Medicine (CCL, RP, VJD), Brigham and Women's
Hospital, Boston, Mass; Medical Genetics Institute (MOG, JIR), Departments ... Cited by 57 - Related articles - BL Direct - All 7 versions
AJ Lusis, AM Fogelman, GC Fonarow - Circulation, 2004 - Am Heart Assoc The optimistic predictions of the impact of genetics on the diagnosis and
prevention of coronary heart disease (CHD) have not been realized, and whether
DNA testing will be incorporated into clinical cardiology practice in the ... Cited by 46 - Related articles - BL Direct - All 7 versions
AJ Jenkins, KG Rowley, TJ Lyons, JD Best, MA … - Current pharmaceutical design, 2004 - ingentaconnect.com AJ Jenkins 1,2,3, * , KG Rowley 1 , TJ Lyons 2,3 , JD Best 1 , MA Hill 2,4 and
RL Klein 3 ... 1 University of Melbourne, Department of Medicine, St Vincent's
Hospital, Melbourne, Australia; ... Endocrinology, Metabolism and ... Cited by 38 - Related articles - BL Direct - All 4 versions
JK Otarod, IJ Goldberg - Current atherosclerosis reports, 2004 - Springer Introduction Hahn [1] first described lipoprotein lipase (LPL) in 1943 when he
observed clearance of postprandial lipemic plasma after heparin injection.
Subsequent studies estab- lished LPL as the primary enzyme required for ... Cited by 37 - Related articles - All 3 versions
MA Cornier, D Dabelea, TL Hernandez, RC … - Endocrine Reviews, 2008 - Endocrine Soc The "metabolic syndrome" (MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS
includes the clustering of abdominal obesity, insulin resistance, ... Cited by 41 - Related articles - All 5 versions
- ►ahajournals.org X Guo, S Cheng, KD Taylor, J Cui, R Hughes, … - Hypertension, 2005 - Am Heart Assoc Insulin resistance is a determinant of blood pressure variation and risk factor
for hypertension. Because insulin resistance and blood pressure cosegregate in
Mexican American families, we thus investigated the association between ... Cited by 34 - Related articles - All 7 versions
- ►ahajournals.org D Wang, H Yang, MJ Quinones, I Bulnes- … - Stroke, 2005 - Am Heart Assoc From the Medical Genetics Institute (DW, HY, KDT, JIR), Steven Spielberg
Pediatric Research Center, Cedars-Sinai Medical Center, Los Angeles, Calif; the
Division of Endocrinology, Diabetes, and Hypertension (MJQ, IE, XJ, RD-LR., ... Cited by 31 - Related articles - All 6 versions
- ►jbc.org KL Pappan, Z Pan, G Kwon, CA Marshall, T … - Journal of Biological Chemistry, 2005 - ASBMB Lipid and glucose metabolism are adversely affected by diabetes, a disease
characterized by pancreatic -cell dysfunction. To clarify the role of lipids in
insulin secretion, we generated mice with -cell-specific overexpression ( ... Cited by 22 - Related articles - All 5 versions
