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Scholar Results 1 - 10 of about 13 citing Carpenter: PKCα is activated but not required during glucose-induced insulin secretion from.... (0.07 sec) 

Protein kinase activation increases insulin secretion by sensitizing the secretory machinery …

- nih.gov
QF Wan, Y Dong, H Yang, X Lou, J Ding, T Xu - Journal of General Physiology, 2004 - jgp.rupress.org
Glucose and other secretagogues are thought to activate a variety of protein
kinases. This study was designed to unravel the sites of action of protein
kinase A (PKA) and protein kinase C (PKC) in modulating insulin secretion. ...
Cited by 35 - Related articles - All 7 versions

Bimodal role of conventional protein kinase C in insulin secretion from rat pancreatic β cells

- nih.gov
H Zhang, M Nagasawa, S Yamada, H Mogami, … - The Journal of Physiology, 2004 - Physiological Soc
The present study was conducted to evaluate the role of conventional protein
kinase C (PKC) in calcium-evoked insulin secretion. In rat β cells transfected
with green fluorescent protein-tagged PKC-α (PKC-α–EGFP), a ...
Cited by 13 - Related articles - All 7 versions

Protein kinase C {delta} plays a non-redundant role in insulin secretion in pancreatic beta …

- jbc.org
T Uchida, N Iwashita, M Ohara-Imaizumi, T … - Journal of Biological Chemistry, 2007 - ASBMB
Protein kinase C (PKC) is considered to modulate glucose-stimulated insulin
secretion. Pancreatic cells express multiple isoforms of PKCs; however, the role
of each isoform in glucose-stimulated insulin secretion remains ...
Cited by 12 - Related articles - All 6 versions

Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats

- rupress.org
T Rose, S Efendic, M Rupnik - Journal of General Physiology, 2007 - jgp.rupress.org
The Goto Kakizaki (GK) rat is a widely used animal model to study defective
glucose-stimulated insulin release in type-2 diabetes (T2D). As in T2D patients,
the expression of several proteins involved in Ca 2+ -dependent exocytosis ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser1917 Is Mediated by Protein …

- jimmunol.org
RI Ludowyke, Z Elgundi, T Kranenburg, JR … - The Journal of Immunology, 2006 - Am Assoc Immnol
Dynamic remodeling of the actinomyosin cytoskeleton is integral to many
biological processes. It is regulated, in part, by myosin phosphorylation.
Nonmuscle myosin H chain IIA is phosphorylated by protein kinase C (PKC) on ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells …

- physiology.org
HA Parkes, E Preston, D Wilks, M … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Accumulation of intracellular lipid in obesity is associated with metabolic
disease in many tissues including liver. Storage of fatty acid as triglyceride
(TG) requires the activation of fatty acids to long-chain acyl-CoAs ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for …

- nih.gov
C Schmitz-Peiffer, TJ Biden - Diabetes, 2008 - Am Diabetes Assoc
Increased lipid availability is strongly associated with both β-cell
dysfunction and insulin resistance, two key facets of type 2 diabetes. Isoforms
of the protein kinase C (PKC) family have been viewed as candidates for ...
Cited by 5 - Related articles - All 4 versions

Ciliary neurotrophic factor promotes survival of neonatal rat islets via the BCL-2 anti- …

- endocrinology-journals.org
LF Rezende, LF Stoppiglia, KLA Souza, A … - Journal of Endocrinology, 2007 - Soc Endocrinology
Ciliary neurotrophic factor (CNTF) belongs to the cytokine family and increases
neuron differentiation and/or survival. Pancreatic islets are richly innervated
and express receptors for nerve growth factors (NGFs) and may undergo ...
Cited by 3 - Related articles - BL Direct - All 2 versions

Ca2 $# x0002b; $# x02013; Secretion Coupling Is Impaired in Diabetic Goto Kakizaki rats


T Rose, S Efendic, M Rupnik - The Journal of General Physiology, 2007 - ukpmc.ac.uk
The Goto Kakizaki (GK) rat is a widely used animal model to study defective
glucose-stimulated insulin release in type-2 diabetes (T2D). As in T2D patients,
the expression of several proteins involved in Ca 2+ -dependent exocytosis ...
Related articles

PKCα tumor suppression in the intestine is associated with transcriptional and translational …


MA Pysz, OV Leontieva, NW Bateman, JM … - Experimental Cell Research, 2009 - Elsevier
Alterations in PKC isozyme expression and aberrant induction of cyclin D1 are
early events in intestinal tumorigenesis. Previous studies have identified
cyclin D1 as a major target in the antiproliferative effects of PKCα in ...
Related articles - All 2 versions


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