PE Cryer - Diabetes, 2005 - Am Diabetes Assoc Iatrogenic hypoglycemia is a problem for people with diabetes. It causes recurrent morbidity,
and sometimes death, as well as a vicious cycle of recurrent hypoglycemia, precluding maintenance
of euglycemia over a lifetime of diabetes. Improved therapeutic approaches that will ... Cited by 75 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org L Kang, AA Dunn-Meynell, VH Routh, LD Gaspers, Y … - Diabetes, 2006 - Am Diabetes Assoc To test the hypothesis that glucokinase is a critical regulator of neuronal glucosensing, glucokinase
activity was increased, using a glucokinase activator drug, or decreased, using RNA interference
combined with calcium imaging in freshly dissociated ventromedial hypothalamic nucleus ... Cited by 49 - Related articles - BL Direct - All 7 versions
- ►angrylapdog.com BE Levin - … Transactions of the Royal Society B: …, 2006 - rstb.royalsocietypublishing.org.p. … Epidemiological studies in humans suggest that maternal undernutrition, obesity and diabetes
during gestation and lactation can all produce obesity in offspring. Animal models have allowed
us to investigate the independent consequences of altering the pre- versus post-natal ... Cited by 42 - Related articles - BL Direct - All 10 versions
- ►nih.gov N Marty, M Dallaporta, M Foretz, M Emery, … - Journal of Clinical …, 2005 - Am Soc Clin Investig Ripglut1;glut2 –/– mice have no endogenous glucose transporter type 2 (glut2) gene expression
but rescue glucose-regulated insulin secretion. Control of glucagon plasma levels is,
however, abnormal, with fed hyperglucagonemia and insensitivity to physiological hypo- ... Cited by 38 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org X Fioramonti, A Lorsignol, A Taupignon, L Pénicaud - Diabetes, 2004 - Am Diabetes Assoc Glucose is known to modify electrical activity of neurons in different hypothalamic areas such
as the arcuate nucleus (ARC) or the ventromedian nucleus. In these structures, it has been demonstrated
that glucose-induced excitation of neurons involves ATP-sensitive K + (K ATP ) channel ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►pubget.com [PDF] J Bryan, A Muñoz, X Zhang, M Düfer, G Drews, P … - Pflügers Archiv European …, 2007 - Springer Abstract The sulfonylurea receptors (SURs) ABCC8/ SUR1 and ABCC9/SUR2 are members
of the C-branch of the transport adenosine triphosphatase superfamily. Unlike their brethren,
the SURs have no identified transport function; instead, evolution has matched these ... Cited by 32 - Related articles - BL Direct - All 6 versions
BE Levin - Physiology & behavior, 2006 - Elsevier The brain and periphery carry on a constant conversation; the periphery informs the brain about
its metabolic needs and the brain provides for these needs through its control of
somatomotor, autonomic and neurohumoral pathways involved in energy intake, ... Cited by 25 - Related articles - All 4 versions
CV Mobbs, F Isoda, H Makimura, J Mastaitis, T Mizuno, … - Physiology & behavior, 2005 - Elsevier Since nutrition-sensitive feedback signals normally act to maintain relatively stable levels of both
available and stored nutritional resources, failure in one or more of these feedback signals could
plausibly lead to obese phenotypes. The glucostatic hypothesis in its original form posited ... Cited by 22 - Related articles - All 4 versions
N Marty, M Dallaporta, B Thorens - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov Neuronal circuits in the central nervous system play a critical role in orchestrating the control
of glucose and energy homeostasis. Glucose, beside being a nutrient, is also a signal detected
by several glucose-sensing units that are located at different anatomical sites and ... Cited by 22 - Related articles - BL Direct - All 4 versions
RH Balfour, AMK Hansen, S Trapp - The Journal of physiology, 2006 - Physiological Soc Several regions of the mammalian brain contain glucosensing neurones. In vivo studies have
suggested that those located in the hypothalamus and lower brainstem are involved in glucoprivic
feeding and homeostatic control of blood glucose. We have identified and characterized ... Cited by 16 - Related articles - BL Direct - All 9 versions
