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Scholar Results 1 - 10 of about 31 citing van den Hoek: Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose.... (0.11 sec) 

Diabetes, obesity, and the brain

- kosen21.org [PDF] 
MW Schwartz, D Porte Jr - Science, 2005 - sciencemag.org
Recent evidence suggests a key role for the brain in the control of both body
fat content and glucose metabolism. Neuronal systems that regulate energy
intake, energy expenditure, and endogenous glucose production sense and ...
Cited by 265 - Related articles - All 12 versions

Central insulin action in energy and glucose homeostasis

- nih.gov
L Plum, BF Belgardt, JC Brüning - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
Insulin has pleiotropic biological effects in virtually all tissues. However,
the relevance of insulin signaling in peripheral tissues has been studied far
more extensively than its role in the brain. An evolving body of evidence ...
Cited by 75 - Related articles - BL Direct - All 11 versions

Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in …

- cell.com
GJ Morton, RW Gelling, KD Niswender, CD … - Cell Metabolism, 2005 - Elsevier
To investigate whether phosphatidylinositol-3 kinase (PI3K) signaling mediates
the metabolic effects of hypothalamic leptin action, adenoviral gene therapy was
used to direct expression of leptin receptors to the area of the ...
Cited by 64 - Related articles - All 9 versions

Physiology and gene regulation of the brain NPY Y1 receptor

- unito.it [PDF] 
C Eva, M Serra, P Mele, GC Panzica, A … - Frontiers in Neuroendocrinology, 2006 - Elsevier
Neuropeptide Y (NPY) is one of the most prominent and abundant neuropeptides in
the mammalian brain where it interacts with a family of G-protein coupled
receptors, including the Y 1 receptor subtype (Y 1 R). NPY-Y 1 R signalling ...
Cited by 37 - Related articles - All 5 versions

Minireview: the brain as a molecular target for diabetic therapy

- endojournals.org
E Prodi, S Obici - Endocrinology, 2006 - Endocrine Soc
Recent evidence highlights the important role of the brain in the control of
glucose homeostasis. Hypothalamic centers sense the availability of peripheral
nutrients via redundant and overlapping nutrient-induced peripheral signals ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice


AC Heijboer, AM van den Hoek, ET Parlevliet, … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 732–738 DOI 10.1007/s00125-006-0138-2 ARTICLE AC
Heijboer . AM van den Hoek . ET Parlevliet . LM Havekes . JA Romijn . ...
Cited by 31 - Related articles - BL Direct - All 3 versions

Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin …

- endojournals.org
MAM den Boer, PJ Voshol, JP Schroder-van … - Endocrinology, 2006 - Endocrine Soc
Several studies have demonstrated an association in humans between plasma levels
or production capacity of the antiinflammatory cytokine IL-10 and insulin
sensitivity. The aim of our study was to investigate the protective role of ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose …

- tno.co.jp [PDF] 
AC Heijboer, AM van den Hoek, H Pijl, PJ … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: The present study was con- ducted to evaluate the
effects of central administration of melanotan II (MTII), a melanocortin-3/4
receptor agonist, on hepatic and whole-body insulin sensitivity, ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Gut-Brain Axis: Regulation of Glucose Metabolism.


AC Heijboer, H Pijl, AM Van den Hoek, LM … - Journal of neuroendocrinology, 2006 - critcaremed.org
Correspondence to: Dr EPM van der Kleij-Corssmit, Leiden University Medical
Center, Department of Endocrinology and Metabolic Diseases, PO Box 9600, 2300 RC
Leiden, The Netherlands (e-mail: epmvan_der_kleij@lumc.nl).
Cited by 12 - Related articles - Cached - BL Direct - All 5 versions

Central resistin induces hepatic insulin resistance via neuropeptide Y

- jneurosci.org
NS Singhal, MA Lazar, RS Ahima - Journal of Neuroscience, 2007 - Soc Neuroscience
Sensing of peripheral hormones and nutrients by the hypothalamus plays an
important role in maintaining peripheral glucose homeostasis. The hormone
resistin impairs the response to insulin in liver and other peripheral ...
Cited by 11 - Related articles - All 3 versions


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