- ►kosen21.org [PDF] MW Schwartz, D Porte Jr - Science, 2005 - sciencemag.org Recent evidence suggests a key role for the brain in the control of both body
fat content and glucose metabolism. Neuronal systems that regulate energy
intake, energy expenditure, and endogenous glucose production sense and ... Cited by 265 - Related articles - All 12 versions
- ►nih.gov L Plum, BF Belgardt, JC Brüning - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Insulin has pleiotropic biological effects in virtually all tissues. However,
the relevance of insulin signaling in peripheral tissues has been studied far
more extensively than its role in the brain. An evolving body of evidence ... Cited by 75 - Related articles - BL Direct - All 11 versions
- ►cell.com GJ Morton, RW Gelling, KD Niswender, CD … - Cell Metabolism, 2005 - Elsevier To investigate whether phosphatidylinositol-3 kinase (PI3K) signaling mediates
the metabolic effects of hypothalamic leptin action, adenoviral gene therapy was
used to direct expression of leptin receptors to the area of the ... Cited by 64 - Related articles - All 9 versions
- ►unito.it [PDF] C Eva, M Serra, P Mele, GC Panzica, A … - Frontiers in Neuroendocrinology, 2006 - Elsevier Neuropeptide Y (NPY) is one of the most prominent and abundant neuropeptides in
the mammalian brain where it interacts with a family of G-protein coupled
receptors, including the Y 1 receptor subtype (Y 1 R). NPY-Y 1 R signalling ... Cited by 37 - Related articles - All 5 versions
- ►endojournals.org E Prodi, S Obici - Endocrinology, 2006 - Endocrine Soc Recent evidence highlights the important role of the brain in the control of
glucose homeostasis. Hypothalamic centers sense the availability of peripheral
nutrients via redundant and overlapping nutrient-induced peripheral signals ... Cited by 32 - Related articles - BL Direct - All 4 versions
AC Heijboer, AM van den Hoek, ET Parlevliet, … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 732–738 DOI 10.1007/s00125-006-0138-2 ARTICLE AC
Heijboer . AM van den Hoek . ET Parlevliet . LM Havekes . JA Romijn . ... Cited by 31 - Related articles - BL Direct - All 3 versions
- ►endojournals.org MAM den Boer, PJ Voshol, JP Schroder-van … - Endocrinology, 2006 - Endocrine Soc Several studies have demonstrated an association in humans between plasma levels
or production capacity of the antiinflammatory cytokine IL-10 and insulin
sensitivity. The aim of our study was to investigate the protective role of ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►tno.co.jp [PDF] AC Heijboer, AM van den Hoek, H Pijl, PJ … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The present study was con- ducted to evaluate the
effects of central administration of melanotan II (MTII), a melanocortin-3/4
receptor agonist, on hepatic and whole-body insulin sensitivity, ... Cited by 13 - Related articles - BL Direct - All 4 versions
AC Heijboer, H Pijl, AM Van den Hoek, LM … - Journal of neuroendocrinology, 2006 - critcaremed.org Correspondence to: Dr EPM van der Kleij-Corssmit, Leiden University Medical
Center, Department of Endocrinology and Metabolic Diseases, PO Box 9600, 2300 RC
Leiden, The Netherlands (e-mail: epmvan_der_kleij@lumc.nl). Cited by 12 - Related articles - Cached - BL Direct - All 5 versions
- ►jneurosci.org NS Singhal, MA Lazar, RS Ahima - Journal of Neuroscience, 2007 - Soc Neuroscience Sensing of peripheral hormones and nutrients by the hypothalamus plays an
important role in maintaining peripheral glucose homeostasis. The hormone
resistin impairs the response to insulin in liver and other peripheral ... Cited by 11 - Related articles - All 3 versions