- ►ualberta.ca [PDF] AN Balamurugan, R Bottino, N Giannoukakis, C … - Pancreas, 2006 - journals.lww.com Abstract: Pancreatic islet cell transplantation is an attractive treatment of type 1 diabetes
(T1D). The success enhanced by the Edmonton protocol has fostered phenomenal progress
in the field of clinical islet transplantation in the past 5 years, with 1-year rates of insulin ... Cited by 31 - Related articles - BL Direct - All 4 versions
SA Ahmad, CJ Wray, HR Rilo, KA Choe, A Gelrud, J … - Current Problems in …, 2006 - Elsevier Chronic pancreatitis is an ongoing inflammatory disorder characterized by irreversible destruction
of the pancreas associated with disabling chronic pain and permanent loss of exocrine and endocrine
function. The apparent incidence of chronic pancreatitis has nearly quadrupled in the past ... Cited by 26 - Related articles - All 4 versions
D Chen, N Zhang, S Fu, B Schröppel, Q Guo, A Garin, … - Diabetes, 2006 - Am Diabetes Assoc Early islet cell loss is a significant problem in clinical islet cell transplantation. Diverse stress
stimuli induce innate immune responses in islets that contribute to β-cell dysfunction,
inflammation, and loss. Here, we show that cytokine-stimulated murine islets express ... Cited by 23 - Related articles - BL Direct - All 6 versions
PPM Rood, R Bottino, AN Balamurugan, C Smetanka … - Transplantation, 2007 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 22 - Related articles - BL Direct - All 3 versions
FM Barbé-Tuana, D Klein, H Ichii, DM Berman, L Coffey … - Diabetes, 2006 - Am Diabetes Assoc Pancreatic islet transplantation is becoming an alternative to insulin therapy in patients suffering
from brittle type 1 diabetes. A major obstacle to the procedure is the early graft loss caused by
nonspecific inflammation at the site of implantation. We recently discovered that CD40, a ... Cited by 21 - Related articles - BL Direct - All 7 versions
AN Balamurugan, J He, F Guo, DB Stolz, … - American Journal of …, 2005 - interscience.wiley.com The isolation process exposes human pancreatic islets to exogenous isolation enzymes. Exposure
to these enzymes, as a result of intraductal injection in the pancreas or simple contact of islets
with enzyme components, causes internalization into the islet cells of enzymes and their ... Cited by 20 - Related articles - BL Direct - All 4 versions
HH Szeto - Antioxidants & Redox Signaling, 2008 - liebertonline.com It is now recognized that oxidative injury and mitochondrial dysfunction are responsible for many
clinical disorders with unmet needs, including ischemia–reperfusion injury,
neurodegeneration, and diabetes. Mito- chondrial dysfunction can lead to cell death by ... Cited by 23 - Related articles - BL Direct - All 4 versions
PPM Rood, R Bottino, AN Balamurugan, Y Fan, DKC … - Pharmaceutical …, 2006 - Springer Received August 30, 2005; accepted October 13, 2005 Abstract. Type 1 diabetes (T1D) is an
autoimmune disease, the clinical onset of which most frequently presents in children and adolescents
who are genetically predisposed. T1D is characterized by specific insulin-producing beta ... Cited by 20 - Related articles - BL Direct - All 4 versions
R Öllinger, H Wang, K Yamashita, B Wegiel, … - Antioxidants & Redox …, 2007 - liebertonline.com Bilirubin is the end product of heme catabolism by heme oxygenases. The inducible form of these
enzymes is heme oxygenase-1 (HO-1), which is the rate-limiting enzyme that can degrade heme
into equimolar quanti- ties of carbon monoxide (CO), biliverdin, and free iron. Biliverdin is ... Cited by 21 - Related articles - All 3 versions
