DD Kim, WC Song - Clinical Immunology, 2006 - Elsevier A number of proteins anchored on the cell surface function to protect host tissues from bystander
injury when complement is activated. In humans, they include decay-accelerating factor
(DAF, CD55), membrane cofactor protein (MCP, CD46), complement receptor 1 (CR1, ... Cited by 52 - Related articles - All 3 versions
TS Kern - Exp Diabetes Res, 2007 - hindawi.com Diabetes causes metabolic and physiologic abnormalities in the retina, and these changes suggest
a role for inflammation in the development of diabetic retinopathy. These changes include upregulation
of iNOS, COX-2, ICAM-1, caspase 1, VEGF, and NF-κB, increased production of nitric ... Cited by 34 - Related articles - View as HTML - All 12 versions
D Turnberg, HT Cook - Current opinion in nephrology and …, 2005 - journals.lww.com Purpose of review The last few years have seen a huge increase in our understanding of the
role of the complement system and its regulation in glomerular disease. Our aim is to summarize
the most important advances in this field. Recent findings The role of complement in ... Cited by 23 - Related articles - All 7 versions
- ►jbc.org Y Huang, CA Smith, H Song, BP Morgan, R … - Journal of Biological …, 2005 - ASBMB CD59 is a 77-amino acid membrane glycoprotein that plays an important role in regulating the
terminal pathway of complement by inhibiting formation of the cytolytic membrane attack complex
(MAC or C5b-9). The MAC is formed by the self assembly of C5b, C6, C7, C8, and ... Cited by 21 - Related articles - BL Direct - All 6 versions
J Østergaard, TK Hansen, S Thiel, A Flyvbjerg - Clinica Chimica Acta, 2005 - Elsevier Diabetes mellitus is a major and increasing health problem worldwide. One of the most serious
consequences of diabetes is the development of diabetic angiopathy, which includes cardiovascular
disease, neuropathy, retinopathy and nephropathy. Diabetic nephropathy alone affects ... Cited by 20 - Related articles - All 5 versions
TK Hansen, MA Gall, L Tarnow, S Thiel, CD … - Archives of Internal …, 2006 - Am Med Assoc Results During follow-up, 169 patients died. The risk of dying was significantly higher among
patients with MBL levels greater than or equal to 1000 µg/L than among patients with levels less
than 1000 µg/L (hazard ratio, 1.5; 95% confidence interval, 1.1-2.1; P = .005). After ... Cited by 19 - Related articles - BL Direct - All 4 versions
X Qin, B Gao - 细胞与分子免疫学: 英文版, 2006 - cmi.ustc.edu.cn The complement system plays an important role in mediating both acquired and innate responses
to defend against microbial infection, and in disposing immunoglobins and apoptotic cells. The
liver (mainly hepatocytes) is responsible for biosynthesis of about 80-90% of plasma ... Cited by 16 - Related articles - View as HTML - All 3 versions
F Fischetti, F Tedesco - Autoimmunity, 2006 - informahealthcare.com The endothelial layer represents a continuous physical barrier that controls coagulation and
allows selective passage of soluble molecules and circulating cells across the vessel wall into
the tissue. The functional activity of the endothelial cells may be influenced by their ... Cited by 15 - Related articles - BL Direct - All 7 versions
KM Brown, SH Sacks, NS Sheerin - Nature Clinical Practice Nephrology, 2007 - eprints.ncl.ac.uk The definitive version of this article is published as: KM Brown;SH Sacks;NS Sheerin. Mechanisms
of disease: the complement system in renal injury--new ways of looking at an old foe. Nat Clin
Pract Nephrol 2007, 3(5), 277-86. ... Mechanisms of Disease: the complement system in ... Cited by 11 - Related articles - View as HTML - BL Direct - All 5 versions
SP Berger, A Roos, MR Daha - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA The complement system is not only an important component of the innate immune system but
it also plays an essential role in the initiation and control of the adaptive immune response. The
three pathways of complement activation converge at the level of C3. Activation of C3 ... Cited by 10 - Related articles - BL Direct - All 6 versions
