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[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN WEISNAGEL,
GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE BOUCHARD. The
human obesity gene map: the 2005 update. Obesity. 2006;14: 529–644. This ...
Cited by 332 - Related articles - View as HTML - All 6 versions

[PDF] The human obesity gene map: the 2004 update


L Perusse, T Rankinen, A Zuberi, YC Chagnon … - Obesity research, 2005 - informatik.hu-berlin.de
Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ...
Cited by 210 - Related articles - View as HTML - All 6 versions

Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early onset …

- auburn.edu [PDF] 
YX Tao - Molecular and cellular endocrinology, 2005 - Elsevier
The neural melanocortin receptors, melanocortin-3 and -4 receptors (MC3R and
MC4R), have been shown to regulate different aspects of energy homeostasis in
rodents. Human genetic studies showed that mutations in the MC4R gene are ...
Cited by 51 - Related articles - All 8 versions

Inactivating mutations of G protein-coupled receptors and diseases: structure-function …

- auburn.edu [PDF] 
YX Tao - Pharmacology and Therapeutics, 2006 - Elsevier
Since the discovery of the first rhodopsin mutation that causes retinitis
pigmentosa in 1990, significant progresses have been made in elucidating the
pathophysiology of diseases caused by inactivating mutations of G protein- ...
Cited by 32 - Related articles - All 7 versions

Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific …

- nih.gov
JL Smart, V Tolle, MJ Low - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
Null mutations of the proopiomelanocortin gene (Pomc –/– ) cause obesity in
humans and rodents, but the contributions of central versus pituitary POMC
deficiency are not fully established. To elucidate these roles, we ...
Cited by 26 - Related articles - BL Direct - All 12 versions

[PDF] Identification and functional characterization of three novel human melanocortin-4 receptor …


R Rong, YX Tao, BM Cheung, A Xu, GC … - CLINICAL ENDOCRINOLOGY-OXFORD-, 2006 - cvm-wwwdev.vetmed.auburn.edu
Objective Mutations in the melanocortin-4 receptor gene (MC4R) are the most
common monogenic form of human obesity. However, the contribution of MC4R
mutations to obesity in Chinese has not been investigated. We studied the ...
Cited by 15 - Related articles - View as HTML - BL Direct - All 7 versions

The single nucleotide polymorphisms of chicken melanocortin-4 receptor (MC4R) gene and …

- scichina.com [PDF] 
X Qiu, N Li, X Deng, X Zhao, Q Meng, X Wang - Science in China Series C: Life Sciences, 2006 - Springer
Abstract Mutations of the melanocortin-4 receptor (MC4R) gene are associated
with the appetite, obesity and growth in pig, mice and human. But little is
known about the function of chicken MC4R gene. In this study, F 2 chicken ...
Cited by 10 - Related articles - BL Direct - All 7 versions

Screening for melanocortin-4 receptor mutations in a cohort of Belgian morbidly obese …


S Beckers, I Mertens, A Peeters, L Van Gaal, … - International journal of obesity, 2006 - cat.inist.fr
Objective: To investigate whether pathogenic melanocortin-4 receptor(MC 4 R)
mutations are a common cause of obesity in Belgium. Design: Cross-sectional
mutation analysis. Subjects: In total, 95 morbidly obese adults(mean age ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional …


J Krakoff, L Ma, S Kobes, WC Knowler, RL … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Among the 3,074 subjects, 43 were heterozygous for R165Q and 14 for
NT100 (frequency = 0.007 and 0.002). Mean (± SD) BMI was higher among subjects
with R165Q (39.3 ± 8.6 kg/m 2 ) or NT100 (41.2 ± 7.8) than subjects ...
Cited by 6 - Related articles - All 4 versions

Molecular mechanism of the constitutive activation of the L250Q human melanocortin-4 …


B Proneth, Z Xiang, ID Pogozheva, SA … - Chemical Biology and Drug Design, 2006 - interscience.wiley.com
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Cited by 5 - Related articles - BL Direct - All 5 versions


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