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Scholar Results 1 - 10 of about 43 citing Nejentsev: Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes. (0.08 sec) 

Vitamin D and diabetes

- sediabetes.org [PDF] 
C Mathieu, C Gysemans, A Giulietti, R … - Diabetologia, 2005 - Springer
Abstract Vitamin D deficiency predisposes individuals to type 1 and type 2
diabetes, and receptors for its activated form—1α,25-dihydroxyvitamin D 3
—have been identified in both beta cells and immune cells. Vitamin D ...
Cited by 126 - Related articles - BL Direct - All 8 versions

Vitamin D and type 1 diabetes mellitus: state of the art

- direct-ms.org [PDF] 
C Mathieu, K Badenhoop - Trends in Endocrinology & Metabolism, 2005 - Elsevier
Recent evidence suggests a role for vitamin D in pathogenesis and prevention of
diabetes mellitus. Active vitamin D, 1α,25(OH) 2 D 3 , prevents type 1 diabetes
in animal models, modifies T-cell differentiation, modulates dendritic cell ...
Cited by 72 - Related articles - All 6 versions

Vitamin D and autoimmunity: new aetiological and therapeutic considerations

- ynet.co.il [PDF] 
Y Arnson, H Amital, Y Shoenfeld - Annals of the rheumatic diseases, 2007 - ard.bmjjournals.com.p.angrylapdog.com
Vitamin D is frequently prescribed by rheumatologists to prevent and treat
osteoporosis. Several observations have shown that vitamin D inhibits
proinflammatory processes by suppressing the enhanced activity of immune ...
Cited by 62 - Related articles - BL Direct - All 8 versions

Type 1 diabetes: pathogenesis and prevention

- ecmaj.com
KM Gillespie - Canadian Medical Association Journal, 2006 - ecmaj.com
Type 1 diabetes results from the autoimmune destruction of insulin-producing ß
cells in the pancreas. Genetic and, as yet undefined, environmental factors act
together to precipitate the disease. The excess mortality associated with ...
Cited by 61 - Related articles - BL Direct - All 13 versions

Vitamin D receptor polymorphisms and diseases

- ujaen.es [PDF] 
JM Valdivielso, E Fernandez - Clinica Chimica Acta, 2006 - Elsevier
The vitamin D endocrine system is central to the control of bone and calcium
homeostasis. Thus, alterations in the vitamin D pathway lead to disturbances in
mineral metabolism. Furthermore, a role for vitamin D has been suggested in ...
Cited by 46 - Related articles - All 4 versions

Vitamin D and human health: lessons from vitamin D receptor null mice

- endojournals.org
R Bouillon, G Carmeliet, L Verlinden, E van … - Endocrine Reviews, 2008 - Endocrine Soc
The vitamin D endocrine system is essential for calcium and bone homeostasis.
The precise mode of action and the full spectrum of activities of the vitamin D
hormone, 1,25-dihydroxyvitamin D [1,25-(OH) 2 D], can now be better ...
Cited by 32 - Related articles - All 6 versions

Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes

- nih.gov
R Bailey, JD Cooper, L Zeitels, DJ Smyth, … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Epidemiological studies have linked vitamin D deficiency with the
susceptibility to type 1 diabetes. Higher levels of the active metabolite
1α,25-dihydroxyvitamin D (1α,25(OH) 2 D) could protect from immune ...
Cited by 28 - Related articles - BL Direct - All 9 versions

Type 1 diabetes in Japan


E Kawasaki, N Matsuura, K Eguchi - Diabetologia, 2006 - Springer
Abstract Type 1 diabetes is a multifactorial disease which results from a
T-cell-mediated autoimmune destruction of the pancreatic beta cells in
genetically predisposed individuals. The risk for individuals of developing ...
Cited by 28 - Related articles - BL Direct - All 3 versions

Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of …

- oxfordjournals.org
SW Guo, VL Magnuson, JJ Schiller, X Wang, … - American journal of epidemiology, 2006 - Oxford Univ Press
Several polymorphisms in the vitamin D receptor (VDR) gene have been reported to
be associated with the risk of developing type 1 diabetes, yet published
findings have been conflicting. In this study, the authors attempted to ...
Cited by 24 - Related articles - BL Direct - All 12 versions

Vitamin D endocrine system and the genetic susceptibility to diabetes, obesity and vascular …

- geno-type.com [PDF] 
AF Reis, OM Hauache, G Velho - Diabetes and Metabolism, 2005 - Elsevier
The Vitamin D endocrine system regulates multiple aspects of calcium metabolism
and cellular differentiation and replication in the immune system, endocrine
pancreas, liver, skeletal muscles and adipocytes. It plays an important ...
Cited by 22 - Related articles - BL Direct - All 4 versions


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