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Scholar Results 1 - 10 of about 38 citing Sasaki: Gene therapy using replication-defective herpes simplex virus vectors expressing.... (0.10 sec) 

HSV-1-derived recombinant and amplicon vectors for gene transfer and gene …


AL Epstein, P Marconi, R Argnani, R … - Current gene …, 2005 - ingentaconnect.com
Abstract: Herpes simplex virus type 1 (HSV-1) is a major human pathogen whose lifestyle is based
on a long-term dual interaction with the infected host characterized by the existence of lytic and
latent infections. Although in most cell types infection with HSV-1 will induce toxic effects ...
Cited by 29 - Related articles - BL Direct - All 3 versions

HSV trafficking and development of gene therapy vectors with applications in the …


AR Frampton, WF Goins, K Nakano, EA Burton, JC … - Gene Therapy, 2005 - nature.com
Herpes simplex virus type 1 (HSV-1) is a neurotropic double-stranded DNA virus that causes
cold sores, keratitis, and rarely encephalitis in humans. Nonpathogenic HSV-1 gene transfer
vectors have been generated by elimination of viral functions necessary for replication. ...
Cited by 24 - Related articles - All 3 versions

Nerve growth factor is critical for cardiac sensory innervation and rescues …

- ahajournals.org
M Ieda, H Kanazawa, Y Ieda, K Kimura, K Matsumura, … - Circulation, 2006 - Am Heart Assoc
Methods and Results— We screened neurotrophic factors and found that cardiac sensory nerves
developed in parallel with NGF synthesized in the heart. Cardiac nociceptive sensory nerves
that were immunopositive for calcitonin gene-related peptide, dorsal root ganglia (DRG), ...
Cited by 16 - Related articles - All 7 versions

Development and application of replication-incompetent HSV-1-based vectors


E Berto, A Bozac, P Marconi - Gene therapy, 2005 - nature.com
The replication-incompetent HSV-1-based vectors are herpesviruses in which genes that are
'essential' for viral replication have been either mutated or deleted. These deletions have substantially
reduced their cytotoxicity by preventing early and late viral gene expression and, together ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Changing concepts of bladder regeneration


A Kanematsu, S Yamamoto, O … - International Journal of …, 2007 - interscience.wiley.com
Abstract: During the last decade, there has been a dramatic increase in studies aimed at regeneration
of the urinary bladder. Many studies employed animal-derived or synthetic materials as grafts
for experimental bladder augmentation models, with or without additional measures to ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Herpes simplex virus vector-mediated delivery of glial cell line-derived …


R Kato, D Wolfe, CH Coyle, S Huang, JB Wechuck, WF … - Gene therapy, 2007 - nature.com
Erectile dysfunction (ED) is frequently associated with injury to the cavernous nerve sustained
during pelvic surgery. Functional recovery from cavernous nerve injury is generally incomplete
and occurs over an extended time frame. We employed a therapeutic gene transfer ...
Cited by 6 - Related articles - BL Direct - All 4 versions

Lower urinary tract symptoms and uroflowmetry in women with type 2 diabetes …


WC Lee, CC Wu, HP Wu, TY Tai - Urology, 2007 - Elsevier
Using a cutoff value of bladder voiding efficiency of less than 75% with a PVR greater than 50
mL but less than 100 mL, a PVR greater than 100 mL, or a total volume greater than 500 mL,
47 patients (25.8%) were stratified as having bladder dysfunction. These patients had a ...
Cited by 6 - Related articles - All 22 versions

Preventive effects of cyclohexenonic long-chain fatty alcohol on diabetic cystopathy …


H Suzuki, M Saito, Y Kinoshita, I Satoh, T … - Canadian journal of …, 2006 - ingentaconnect.com
Abstract: In this study, we investigated the preventive effect of n-hexacosanol on diabetes-induced
bladder dysfunction in the rat. Diabetes was induced in 8-week-old male Sprague–Dawley rats
by administering an injection of streptozotocin (50 mg/kg, ip). The rats were randomly ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Proteomics analysis identifies molecular targets related to diabetes mellitus- …

- nih.gov
E Yohannes, J Chang, GJ Christ, KP Davies, MR … - Molecular and Cellular …, 2008 - ASBMB
Page 1. 1 Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus
Associated Bladder Dysfunction. 1 Elizabeth Yohannes, 1 Jinsook Chang, 2 George
J. Christ, 3 Kelvin P. Davies, 1* Mark R. Chance. 1Case ...
Cited by 5 - Related articles - All 5 versions

An update on gene therapy/transfer treatments for bladder dysfunction


GJ Christ, SJ Hodges, A Melman - Current Bladder Dysfunction Reports, 2006 - Springer
Urinary Incontinence: A Manifestation of Unchecked Bladder Dysfunction and Disease There
are a plethora of potential diseases and conditions that affect the bladder and ultimately can
lead to urinary incontinence or the involuntary leakage of urine from the bladder. Urinary ...
Cited by 4 - Related articles - BL Direct


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