- ►jimmunol.org J Allison, HE Thomas, T Catterall, TWH Kay, A … - The Journal of Immunology, 2005 - Am Assoc Immnol In type 1 diabetes, many effector mechanisms damage the cell, a key one being
perforin/granzyme B production by CD8 + T cells. The death receptor pathway has
also been implicated in cell death, and we have therefore generated NOD ... Cited by 24 - Related articles - All 7 versions
- ►jimmunol.org H Bour-Jordan, HL Thompson, JA Bluestone - The Journal of Immunology, 2005 - Am Assoc Immnol NOD mice deficient for the costimulatory molecule B7-2 (NOD-B7-2KO mice) are
protected from autoimmune diabetes but develop a spontaneous autoimmune
peripheral neuropathy that resembles human diseases Guillain-Barre syndrome ... Cited by 18 - Related articles - BL Direct - All 4 versions
M Pearl-Yafe, A Kaminitz, ES Yolcu, I Yaniv, … - Current pharmaceutical design, 2007 - ingentaconnect.com Abstract: Abundant information is available on the involvement of various
cellular and molecular mechanisms in cell apoptosis. The experimental evidence
is controversial and difficult to reconcile, and the mechanisms of evasion ... Cited by 17 - Related articles - BL Direct - All 3 versions
M Pearl-Yafe, ES Yolcu, I Yaniv, J Stein, H … - BioEssays, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►amjpathol.org AS Mohamood, ML Guler, Z Xiao, D Zheng, A … - American Journal of Pathology, 2007 - ASIP Spontaneous mutation of Fas (lpr) or FasL (gld) completely protects nonobese
diabetic mice from autoimmune diabetes but also causes massive double-negative
T-cell lymphoproliferation. In this study, we used bone marrow chimeras and ... Cited by 6 - Related articles - BL Direct - All 11 versions
A Kaminitz, J Stein, I Yaniv, N Askenasy - Immunology and Cell Biology, 2007 - nature.com Autoimmune insulitis, the cause of type 1 diabetes, evolves through several
discrete stages that culminate in -cell death. In the first stage, antigenic
epitopes of B-cell-specific peptides are processed by antigen presenting ... Cited by 3 - Related articles - All 3 versions
R Bergholdt, AE Karlsen, PH Hagedorn, M … - Genes and Immunity, 2007 - nature.com We recently finemapped a type 1 diabetes (T1D)-linked region on chromosome 21,
indicating that one or more T1D-linked genes exist in this region with 33
annotated genes. In the current study, we have taken a novel approach using ... Cited by 1 - Related articles - BL Direct - All 3 versions
E Angstetra, KL Graham, S Emmett, NL Dudek … - Immunology and Cell Biology, 2008 - nature.com CD4 + T cells can actively kill -cells in type I diabetes as well as help CD8 +
T cells become cytolytic. Cytokines have the potential to kill -cells, or
upregulate Fas on -cells, and increase their susceptibility to FasL. We ... Related articles - All 2 versions
… ОМ Смирнова, СМ Степанова, ЛП Алексеев - Сахарный диабет, 2006 - elibrary.ru Центральным механизмом гибели р-клеток
поджелудочной железы при сахарном диабете 1
типа (СД1) в настоящее время считается ... Related articles