- ►shouxi.net AM Shapiro, C Ricordi, BJ Hering, H … - New England Journal …, 2006 - content.nejm.org AM James Shapiro, MD, Ph.D., Camillo Ricordi, MD, Bernhard J. Hering, MD, Hugh
Auchincloss, MD, Robert Lindblad, MD, R. Paul Robertson, MD, Antonio Secchi, MD, Mathias
D. Brendel, MD, Thierry Berney, MD, Daniel C. Brennan, MD, Enrico Cagliero, MD, ... Cited by 395 - Related articles - BL Direct - All 9 versions
- ►hematologylibrary.org LO Mosnier, BV Zlokovic, JH Griffin - Blood, 2007 - bloodjournal.hematologylibrary.org Protein C is best known for its mild deficiency associated with venous thrombosis risk and severe
deficiency associated with neonatal purpura fulminans. Activated protein C (APC) anticoagulant
activity involves proteolytic inactivation of factors Va and VIIIa, and APC resistance is ... Cited by 133 - Related articles - BL Direct - All 4 versions
- ►endojournals.org R Granata, F Settanni, L Biancone, L Trovato, R Nano, … - Endocrinology, 2007 - Endocrine Soc Among its pleiotropic actions, ghrelin modulates insulin secretion and glucose metabolism. Herein
we investigated the role of ghrelin in pancreatic ß-cell proliferation and apoptosis induced by
serum starvation or interferon (IFN)- /TNF- , whose synergism is a major cause for ß-cell ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET Islet transplantation may be used to treat type I diabetes. Despite tremendous progress in islet
isolation, culture, and preservation, the clinical use of this modality of treatment is limited due
to post-transplantation challenges to the islets such as the failure to revascularize and ... Cited by 32 - Related articles - BL Direct - All 13 versions
- ►diabetesjournals.org JA Emamaullee, AM Shapiro - Diabetes, 2006 - Am Diabetes Assoc A substantial proportion of the transplanted islet mass fails to engraft due to death by
apoptosis, and a number of strategies have been explored to inhibit β-cell loss. Inhibition of extrinsic
signals of apoptosis (ie, cFLIP or A20) have been explored in experimental islet ... Cited by 31 - Related articles - BL Direct - All 10 versions
LO Mosnier, JH Griffin - Front Biosci, 2006 - bioscience.org 1. Abstract 2. Introduction 3. History of the protein C pathway 4. Components of the protein C
pathway 4.1. Protein C 4.2. Thrombomodulin 4.3. Endothelial protein C receptor 4.4. Protein
S 4.5. Factor V 4.6. Factor VIII 5. The anticoagulant protein C pathway 5.1. Activation of ... Cited by 28 - Related articles - View as HTML - All 2 versions
- ►diabetesjournals.org S Cabric, J Sanchez, T Lundgren, A Foss, M Felldin, R … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—In clinical islet transplantation, the instant blood-mediated inflammatory reaction
(IBMIR) is a major factor contributing to the poor initial engraftment of the islets. This reaction
is triggered by tissue factor and monocyte chemoattractant protein (MCP)-1, expressed by ... Cited by 24 - Related articles - BL Direct - All 7 versions
GGM Pinkse, WP Bouwman, R Jiawan-Lalai, OT … - Diabetes, 2006 - Am Diabetes Assoc Islet transplantation is associated with a high rate of early graft failure caused by early immune
attack and poor functionality of islets. Apoptosis of islet cells appears soon after islet isolation
and primarily involves the β-cell. The purpose of this study was to determine the effect of ... Cited by 24 - Related articles - BL Direct - All 6 versions
D vanderwindt, R Bottino, A Casu, N … - …, 2007 - interscience.wiley.com Abstract: Islets isolated from multiple pancreas donors are often necessary to achieve euglycemia
in type 1 diabetic patients treated by islet allotransplantation. This increases the burden on the
limited pool of donor organs. After infusion into the portal vein, a substantial percentage of ... Cited by 17 - Related articles - BL Direct - All 3 versions
D Yin, JW Ding, J Shen, L Ma, M Hara, AS … - American Journal of …, 2006 - ccmjournal.org From University Health Network, Women's Health Program (JIC, AMC), Inter-Departmental Division
of Critical Care Medicine (MSH), Department of Medicine (MSH, CMT, AMC), and Krembil Neuroscience
Program (MPM); University of Toronto, Institute of Medical Science (JIC, MSH, CMT), ... Cited by 17 - Related articles - BL Direct - All 4 versions
