J He, I Usui, K Ishizuka, Y Kanatani, K … - Molecular Endocrinology, 2006 - Endocrine Soc Proinflammatory cytokines are recently reported to inhibit insulin signaling
causing insulin resistance. IL-1 is also one of the proinflammatory cytokines;
however, it has not been clarified whether IL-1 may also cause insulin ... Cited by 24 - Related articles - BL Direct - All 3 versions
- ►jbc.org KH Yew, M Hembree, K Prasadan, B Preuett, C … - Journal of Biological Chemistry, 2005 - ASBMB A key goal of cellular engineering is to manipulate progenitor cells to become
-cells, allowing cell replacement therapy to cure diabetes mellitus. As a
paradigm for cell engineering, we have studied the molecular mechanisms by ... Cited by 15 - Related articles - BL Direct - All 5 versions
B Ahrén - Current Opinion in Endocrinology, Diabetes and …, 2006 - journals.lww.com Recent findings: Glucagon-like peptide 1 and glucose-dependent insulinotropic
polypeptide are released from the gut after meal ingestion; the release of
glucagon-like peptide 1 is slightly impaired in individuals with type 2 ... Cited by 4 - Related articles - BL Direct - All 2 versions
- ►biologists.org CV Esguerra, L Nelles, L Vermeire, A … - Development, 2007 - dev.biologists.org During vertebrate development, signaling by the TGFβ ligand Nodal is critical
for mesoderm formation, correct positioning of the anterior-posterior axis,
normal anterior and midline patterning, and left-right asymmetric ... Cited by 4 - Related articles - BL Direct - All 5 versions
E Tei, S Mehta, SS Tulachan, H Yew, M … - Pancreas, 2005 - journals.lww.com Objectives: Glucagon-like peptide-1 (GLP-1) is known to stimulate
glucose-dependent insulin production and secretion by pancreatic b-cells.
Preliminary evidence suggests that GLP-1 may also influence endocrine ... Cited by 3 - Related articles - BL Direct - All 3 versions
S Mehta, GK Gittes - Journal of Hepato-Biliary-Pancreatic Surgery, 2005 - Springer There is a significant amount of data that supports a role for transforming
growth factor (TGF-b) superfamily signaling in pancreatic differentiation. Many
of the sub- families of the superfamily have been implicated in nu- merous ... Cited by 2 - Related articles - All 3 versions
CJ Rhodes - Pancreatic Beta Cell in Health and Disease, 2007 - Springer Summary. Pancreatic beta-cell mass, under normal circumstances, is main- tained
at an optimal level to provide for a normal metabolic load. It should not be
viewed as static, and slow in turning over. Indeed, the adult beta-cells ... Related articles - All 2 versions