- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
PE MacDonald, YZ De Marinis, R Ramracheya, … - PLoS Biol, 2007 - biology.plosjournals.org Glucagon, secreted from pancreatic islet α cells, stimulates gluconeogenesis
and liver glycogen breakdown. The mechanism regulating glucagon release is
debated, and variously attributed to neuronal control, paracrine control by ... Cited by 25 - Related articles - Cached - All 7 versions
E Flodgren, B Olde, S Meidute-Abaraviciene, … - Biochemical and Biophysical Research …, 2007 - Elsevier The free fatty acid receptor, GPR40, has been coupled with insulin secretion via
its expression in pancreatic β-cells. However, the role of GPR40 in the release
of glucagon has not been studied and previous attempts to identify the ... Cited by 15 - Related articles - All 5 versions
- ►shouxi.net CS Olofsson, S Collins, M Bengtsson, L … - Diabetes, 2007 - Am Diabetes Assoc Mouse β-cells cultured at 15 mmol/l glucose for 72 h had reduced ATP-sensitive
K + (K ATP ) channel activity (−30%), increased voltage-gated Ca 2+ currents,
higher intracellular free Ca 2+ concentration ([Ca 2+ ] i ; +160%), more ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] LA Stoddart, NJ Smith, G Milligan - Pharmacological reviews, 2008 - ASPET Identification of G protein-coupled receptors that are activated by free fatty
acids has led to considerable interest in their pharmacology and function
because of the wide range of normal physiology and disease states in which ... Cited by 9 - Related articles - All 5 versions
J Hong, R Abudula, J Chen, PB Jeppesen, … - Metabolism, 2005 - Elsevier The influence of fatty acids on beta cell function has been well established
whereas little is known about the role of fatty acids on alpha cell function.
The aim of our study was to investigate the short-term effects of chain ... Cited by 9 - Related articles - All 9 versions
- ►endocrinology-journals.org I Quesada, E Tuduri, C Ripoll, A Nadal - Journal of Endocrinology, 2008 - Soc Endocrinology The secretion of glucagon by pancreatic -cells plays a critical role in the
regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes
insulin actions by stimulating hepatic glucose synthesis and mobilization, ... Cited by 8 - Related articles - All 3 versions
- ►endojournals.org F Xia, YM Leung, G Gaisano, X Gao, Y Chen, … - Endocrinology, 2007 - Endocrine Soc Pancreatic -cells secrete glucagon in response to low glucose to counter insulin
actions, thereby maintaining glucose homeostasis. The molecular basis of -cell
stimulus-secretion coupling has not been fully elucidated. We investigated ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►cell.com P Rorsman, SA Salehi, F Abdulkader, M … - Trends in Endocrinology & Metabolism, 2008 - Elsevier Glucagon, secreted by the α-cells of the pancreatic islets, is the most
important glucose-increasing hormone of the body. The precise regulation of
glucagon release remains incompletely defined but has been proposed to ... Cited by 4 - Related articles - All 5 versions
- ►physiology.org Y Tian, RF Corkey, GC Yaney, PB Goforth, LS … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Nonesterified fatty acids such as oleate and palmitate acutely potentiate
insulin secretion from pancreatic islets in a glucose-dependent manner. In
addition, recent studies show that fatty acids elevate intracellular free ... Cited by 3 - Related articles - All 4 versions