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Scholar Results 1 - 10 of about 22 citing Olofsson: Palmitate stimulation of glucagon secretion in mouse pancreatic α-cells results.... (0.09 sec) 

{alpha}-Cells of the endocrine pancreas: 35 years of research but the enigma remains

- endojournals.org
J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc
Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ...
Cited by 60 - Related articles - BL Direct - All 4 versions

AK ATP channel-dependent pathway within alpha cells regulates glucagon release from …


PE MacDonald, YZ De Marinis, R Ramracheya, … - PLoS Biol, 2007 - biology.plosjournals.org
Glucagon, secreted from pancreatic islet α cells, stimulates gluconeogenesis
and liver glycogen breakdown. The mechanism regulating glucagon release is
debated, and variously attributed to neuronal control, paracrine control by ...
Cited by 25 - Related articles - Cached - All 7 versions

GPR40 is expressed in glucagon producing cells and affects glucagon secretion


E Flodgren, B Olde, S Meidute-Abaraviciene, … - Biochemical and Biophysical Research …, 2007 - Elsevier
The free fatty acid receptor, GPR40, has been coupled with insulin secretion via
its expression in pancreatic β-cells. However, the role of GPR40 in the release
of glucagon has not been studied and previous attempts to identify the ...
Cited by 15 - Related articles - All 5 versions

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion …

- shouxi.net
CS Olofsson, S Collins, M Bengtsson, L … - Diabetes, 2007 - Am Diabetes Assoc
Mouse β-cells cultured at 15 mmol/l glucose for 72 h had reduced ATP-sensitive
K + (K ATP ) channel activity (−30%), increased voltage-gated Ca 2+ currents,
higher intracellular free Ca 2+ concentration ([Ca 2+ ] i ; +160%), more ...
Cited by 10 - Related articles - BL Direct - All 5 versions

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1,-2, and-3: …

- pubget.com [PDF] 
LA Stoddart, NJ Smith, G Milligan - Pharmacological reviews, 2008 - ASPET
Identification of G protein-coupled receptors that are activated by free fatty
acids has led to considerable interest in their pharmacology and function
because of the wide range of normal physiology and disease states in which ...
Cited by 9 - Related articles - All 5 versions

The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, …


J Hong, R Abudula, J Chen, PB Jeppesen, … - Metabolism, 2005 - Elsevier
The influence of fatty acids on beta cell function has been well established
whereas little is known about the role of fatty acids on alpha cell function.
The aim of our study was to investigate the short-term effects of chain ...
Cited by 9 - Related articles - All 9 versions

Physiology of the pancreatic {alpha}-cell and glucagon secretion: role in glucose …

- endocrinology-journals.org
I Quesada, E Tuduri, C Ripoll, A Nadal - Journal of Endocrinology, 2008 - Soc Endocrinology
The secretion of glucagon by pancreatic -cells plays a critical role in the
regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes
insulin actions by stimulating hepatic glucose synthesis and mobilization, ...
Cited by 8 - Related articles - All 3 versions

Targeting of Voltage-Gated K+ and Ca2+ Channels and Soluble N-Ethylmaleimide-Sensitive …

- endojournals.org
F Xia, YM Leung, G Gaisano, X Gao, Y Chen, … - Endocrinology, 2007 - Endocrine Soc
Pancreatic -cells secrete glucagon in response to low glucose to counter insulin
actions, thereby maintaining glucose homeostasis. The molecular basis of -cell
stimulus-secretion coupling has not been fully elucidated. We investigated ...
Cited by 7 - Related articles - BL Direct - All 3 versions

KATP-channels and glucose-regulated glucagon secretion

- cell.com
P Rorsman, SA Salehi, F Abdulkader, M … - Trends in Endocrinology & Metabolism, 2008 - Elsevier
Glucagon, secreted by the α-cells of the pancreatic islets, is the most
important glucose-increasing hormone of the body. The precise regulation of
glucagon release remains incompletely defined but has been proposed to ...
Cited by 4 - Related articles - All 5 versions

Differential modulation of L-type calcium channel subunits by oleate

- physiology.org
Y Tian, RF Corkey, GC Yaney, PB Goforth, LS … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Nonesterified fatty acids such as oleate and palmitate acutely potentiate
insulin secretion from pancreatic islets in a glucose-dependent manner. In
addition, recent studies show that fatty acids elevate intracellular free ...
Cited by 3 - Related articles - All 4 versions


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