LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com Obesity increases the risk of cardiovascular disease and premature death.
Adipose tissue releases a large number of bioactive mediators that influence not
only body weight homeostasis but also insulin resistance — the core ... Cited by 261 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org AJG Hanley, K Williams, A Festa, LE … - Diabetes, 2005 - Am Diabetes Assoc Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the
metabolic syndrome, although it is not known whether markers of NAFLD, including
elevated concentrations of aspartate aminotransferase (AST), alanine ... Cited by 117 - Related articles - BL Direct - All 6 versions
RK Schindhelm, JM Dekker, G Nijpels, LM … - Atherosclerosis, 2007 - Elsevier Alanine aminotransferase (ALT) is a marker of non-alcoholic fatty liver disease
(NAFLD) and predicts incident type 2 diabetes mellitus (DM2). Recently, ALT was
shown to be also associated with endothelial dysfunction and carotid ... Cited by 88 - Related articles - All 18 versions
G Targher, G Arcaro - Atherosclerosis, 2007 - Elsevier Non-alcoholic fatty liver disease (NAFLD) is present in up to one-third of the
general population and in the majority of patients with cardio-metabolic risk
factors such as abdominal obesity, type 2 diabetes and other components of ... Cited by 89 - Related articles - All 18 versions
G Musso, R Gambino, G Biroli, M Carello, E … - American Journal of Gastroenterology, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 85 - Related articles - BL Direct - All 6 versions
- ►endojournals.org TS Burgert, SE Taksali, J Dziura, TR … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Findings: Elevated ALT (>35 U/liter) was found in 14% of adolescents, with a
predominance of male gender and white/Hispanic race/ethnicity. After adjusting
for potential confounders, rising ALT was associated with reduced insulin ... Cited by 77 - Related articles - BL Direct - All 6 versions
M Roden - Nature Reviews Endocrinology, 2006 - nature.com Hepatic steatosis is defined by an increased content of hepatocellular lipids
(HCLs) and is frequently observed in insulin-resistant states including type 2
diabetes mellitus. A dietary excess of saturated fat contributes ... Cited by 73 - Related articles - BL Direct - All 4 versions
RK Schindhelm, M Diamant, JM Dekker, ME … - Diabetes/Metabolism Reviews - interscience.wiley.com For a long time, hepatic steatosis was believed to be a benign condition. Only
recently, liver steatosis, also termed non-alcoholic fatty liver disease
(NAFLD), has gained much interest. In most cases of NAFLD, a condition ... Cited by 63 - Related articles - BL Direct - All 3 versions
M Kolak, J Westerbacka, VR Velagapudi, D … - Diabetes, 2007 - Am Diabetes Assoc RESULTS— Expression levels of the macrophage marker CD68, the chemokines
monocyte chemoattractant protein-1 and macrophage inflammatory protein-1α, and
plasminogen activator inhibitor-1 were significantly increased, and those ... Cited by 44 - Related articles - BL Direct - All 10 versions
- ►nursing2008.com RK Schindhelm, M Diamant, SJL Bakker, R Van … - European journal of clinical investigation, 2005 - pt.wkhealth.com Background: Plasma levels of liver transaminases, including alanine
aminotransferase (ALT), are elevated in most cases of nonalcoholic fatty liver
disease (NAFLD). Elevated ALT levels are associated with insulin ... Cited by 40 - Related articles - All 7 versions
