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Scholar Results 1 - 10 of about 27 citing Iossa: A possible link between skeletal muscle mitochondrial efficiency and age-induced insulin.... (0.10 sec) 

Peroxisome proliferator-activated receptor-{gamma} co-activator 1 {alpha}-mediated …

- jbc.org
TR Koves, P Li, J An, T Akimoto, D Slentz, … - Journal of Biological Chemistry, 2005 - ASBMB
Peroxisome proliferator-activated receptor- co-activator 1 (PGC1 ) is a
promiscuous co-activator that plays a key role in regulating mitochondrial
biogenesis and fuel homeostasis. Emergent evidence links decreased skeletal ...
Cited by 104 - Related articles - BL Direct - All 4 versions

Pathophysiology of nonalcoholic steatohepatitis

- ccf.org [PDF] 
AJ McCullough - Journal of Clinical Gastroenterology, 2006 - journals.lww.com
Abstract: Nonalcoholic fatty liver disease (NAFLD) affects ap- proximately 30%
of adults and 20% of children in the United States. Nonalcoholic steatohepatitis
(NASH) is its most severe histologic form and progresses to cirrhosis in ...
Cited by 96 - Related articles - BL Direct - All 5 versions

Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes

- shouxi.net
M Mogensen, K Sahlin, M Fernström, D … - Diabetes, 2007 - Am Diabetes Assoc
We tested the hypothesis of a lower respiratory capacity per mitochondrion in
skeletal muscle of type 2 diabetic patients compared with obese subjects. Muscle
biopsies obtained from 10 obese type 2 diabetic and 8 obese nondiabetic ...
Cited by 50 - Related articles - BL Direct - All 6 versions

Hepatic insulin gene therapy prevents deterioration of vascular function and improves …

- physiology.org
PM Thule, AG Campbell, DJ Kleinhenz, DE … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Hepatic insulin gene therapy (HIGT) ameliorates hyperglycemia in diabetic
rodents, suggesting that similar approaches may eventually provide a means to
improve treatment of diabetes mellitus. However, whether the metabolic and ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Pathogenesis of non-alcoholic steatohepatitis: human data

- ccf.org [PDF] 
J Edmison, AJ McCullough - Clinics in liver disease, 2007 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has moved rapidly to the forefront of
clinical disease, with a prevalence of 30% in the adult United States population
and a definite but yet uncertain rate of progression to cirrhosis and ...
Cited by 20 - Related articles - All 18 versions

Altered skeletal muscle subsarcolemmal mitochondrial compartment during catch-up fat after …

- shouxi.net
R Crescenzo, L Lionetti, MP Mollica, M Ferraro, … - Diabetes, 2006 - Am Diabetes Assoc
An accelerated rate of fat recovery (catch-up fat) and insulin resistance are
characteristic features of weight recovery after caloric restriction, with
implications for the pathophysiology of catch-up growth and weight ...
Cited by 18 - Related articles - BL Direct - All 6 versions

[PDF] Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, …


CX Fang, TA Doser, X Yang, N Sreejayan, J … - Aging Cell, 2006 - uwyo.edu
Aging is often accompanied by reduced insulin sensitivity and cardiac
dysfunction. However, the causal relationship between the two remains poorly
understood. This study was designed to determine the impact of ...
Cited by 16 - Related articles - View as HTML - All 4 versions

Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing …


W Qiang, K Weiqiang, Z Qing, Z Pengju, L Yi - Experimental & molecular medicine, 2007 - ncbi.nlm.nih.gov
Insufficient intracellular fat oxidation is an important contributor to
aging-related insulin resistance, while the precise mechanism underlying is
unclear. AMP-activated protein kinase (AMPK) is an important regulator of ...
Cited by 12 - Related articles - BL Direct - All 9 versions

Peroxisome proliferator-activated receptor-co-activator 1-mediated metabolic remodeling of …

- shouxi.net
TR Koves, P Li, J An, T Akimoto, D Slentz, … - J. Biol. Chem, 2005 - ASBMB
Peroxisome proliferator-activated receptor- co-activator 1 (PGC1 ) is a
promiscuous co-activator that plays a key role in reg- ulating mitochondrial
biogenesis and fuel homeostasis. Emergent evidence links decreased skeletal ...
Cited by 13 - Related articles - All 2 versions

Positive Effects of 17 {beta}-Estradiol on Insulin Sensitivity in Aged Ovariectomized Female …


A Alonso, R Fernandez, M Moreno, P Ordonez … - Journals of Gerontology Series A: Biological and …, 2006 - Geron Soc America
Aging is associated with insulin resistance, which represents a common factor in
age-related diseases. We aimed to determine the role of 17ß-estradiol on
insulin sensitivity and memory during aging using ovariectomized rats ...
Cited by 12 - Related articles - BL Direct - All 3 versions


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