- ►endojournals.org Y Toyoshima, O Gavrilova, S Yakar, W Jou, S Pack, Z … - Endocrinology, 2005 - Endocrine Soc Leptin has metabolic effects on peripheral tissues including muscle, liver, and pancreas, and
it has been successfully used to treat lipodystrophic diabetes, a leptin-deficient state. To study
whether leptin therapy can be used for treatment of more common cases of type 2 ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►endojournals.org P Pennisi, O Gavrilova, J Setser-Portas, W Jou, S … - Endocrinology, 2006 - Endocrine Soc IGF-I and insulin are structurally related polypeptides that mediate a similar pattern of biological
effects via receptors that display considerably homology. Administration of recombinant human
IGF-I (rhIGF-I) has been proven to improve glucose control and liver and muscle insulin ... Cited by 19 - Related articles - BL Direct - All 5 versions
Z Asghar, D Yau, F Chan, D Leroith, CB Chan, MB … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Although insulin resistance induces compensatory increases in beta
cell mass and function to maintain normoglycaemia, it is not clear wheth- er insulin resistance
can precipitate beta cell dysfunction and hyperglycaemia without a pre-existing beta cell ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►nih.gov H Ying, O Araki, F Furuya, Y Kato, SY … - Molecular and cellular …, 2007 - Am Soc Microbiol Thyroid hormone (T3) is critical for growth, differentiation, and maintenance of metabolic
homeostasis. Mice with a knock-in mutation in the thyroid hormone receptor gene (TR 1PV) were
created previously to explore the roles of mutated TR 1 in vivo. TR 1PV is a dominant ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►physiology.org CH Kim, P Pennisi, H Zhao, S Yakar, JB … - American Journal of …, 2006 - Am Physiological Soc Most rodent models of insulin resistance are accompanied by decreased circulating adiponectin
levels. Adiponectin treatment improves the metabolic phenotype by increasing fatty acid oxidation
in skeletal muscle and suppressing hepatic glucose production. Muscle IGF-I receptor ... Cited by 14 - Related articles - BL Direct - All 4 versions
E Meezan, EM Meezan, K Jones, R Moore, S … - Journal of Agricultural and …, 2005 - uab.edu Puerarin and daidzin are the major isoflavone glucosides found in kudzu dietary
supplements. In this study, we demonstrated that puerarin significantly improves glucose tolerance
in C57BL/6J-ob/ob mice, an animal model of type 2 diabetes mellitus, blunting the rise in ... Cited by 12 - Related articles - View as HTML - All 8 versions
T Takamura, M Sakurai, M Nakamura, A Shimizu, T … - Diabetes research and …, 2007 - Elsevier A rapid-acting insulin analog was administered at each mealtime to 40 Japanese patients with
type 2 diabetes whose existing antidiabetic medication was discontinued. Approximately
one-half (52.5%) of the patients achieved a minimum early morning FPG levels ... Cited by 5 - Related articles - All 15 versions
AG Gómez-Valadés, A Méndez-Lucas, A Vidal-Alabró, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Treatment resulted in reduced PEPCK-C mRNA and protein. After treatment, improved
glycemia and insulinemia, lower triglyceride, and higher total and HDL cholesterol were
measured. Unsterified fatty acid accumulation was observed in the liver, in the absence of ... Cited by 5 - Related articles - All 5 versions
