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Scholar Results 1 - 10 of about 37 citing Gibson: Genetics of the APM1 locus and its contribution to type 2 diabetes susceptibility.... (0.09 sec) 

Adiponectin-a key adipokine in the metabolic syndrome


JP Whitehead, AA Richards, IJ Hickman, GA … - Diabetes Obesity and Metabolism, 2006 - pt.wkhealth.com
Adiponectin is a recently described adipokine that has been recognized as a key
regulator of insulin sensitivity and tissue inflammation. It is produced by
adipose tissue (white and brown) and circulates in the blood at very high ...
Cited by 130 - Related articles - BL Direct - All 6 versions

Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and …

- shouxi.net
IM Heid, SA Wagner, H Gohlke, B Iglseder, JC … - Diabetes, 2006 - Am Diabetes Assoc
The associations of the adiponectin (APM1) gene with parameters of the metabolic
syndrome are inconsistent. We performed a systematic investigation based on
fine-mapped single nucleotide polymorphisms (SNPs) highlighting the genetic ...
Cited by 52 - Related articles - BL Direct - All 6 versions

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular …

- diabetesjournals.org
C Menzaghi, V Trischitta, A Doria - Diabetes, 2007 - Am Diabetes Assoc
Recent evidence points to molecules secreted by the adipose tissue, or
adipokines, as possible links between increased adipose mass and metabolic
abnormalities. Among these molecules, adiponectin has drawn much attention ...
Cited by 52 - Related articles - BL Direct - All 9 versions

Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic …

- darkmay.cz [PDF] 
DR Gable, SJ Hurel, SE Humphries - Atherosclerosis, 2006 - Elsevier
The increasing prevalence of obesity and metabolic syndrome/insulin resistance
has attracted considerable interest due to their identification as risk factors
for cardiovascular disease and, hence, targets for cardiovascular disease ...
Cited by 40 - Related articles - All 15 versions

Human genetics of adiponectin in the metabolic syndrome


WS Yang, LM Chuang - Journal of molecular medicine, 2006 - Springer
Abstract Adiponectin, an adipose-derived plasma protein, has been well
established to be an important biomarker for metabolic syndrome and its
complications after exhausted studies in humans. Animal and cell culture ...
Cited by 34 - Related articles - BL Direct - All 4 versions

Possible relations between the polymorphisms of the cytokines IL-19, IL-20 and IL-24 and …


S Koks, K Kingo, K Vabrit, R Rätsep, M … - Genes and immunity, 2005 - nature.com
The aim of present study was to elucidate the role of the interleukin (IL)-24
gene in predicting risk for plaque-type psoriasis and to describe the linkage
disequilibrium (LD) pattern emerging from the genes of IL-19, IL-20 and ...
Cited by 28 - Related articles - BL Direct - All 3 versions

The genetic basis of type 2 diabetes


SK Das, SC Elbein - Cellscience, 2006 - pubmedcentral.nih.gov
Type 2 Diabetes results from a complex physiologic process that includes the
pancreatic beta cells, peripheral glucose uptake in muscle, the secretion of
multiple cytokines and hormone-like molecules from adipocytes, hepatic ...
Cited by 25 - Related articles - All 3 versions

A synonymous coding polymorphism in the α2-Heremans-Schmid glycoprotein gene is …

- shouxi.net
A Siddiq, F Lepretre, S Hercberg, P Froguel, … - Diabetes, 2005 - Am Diabetes Assoc
AHSG is a multifunctional protein with diverse biological functions that include
the regulation of calcium homeostasis (6,7). A possible role for AHSG in
influencing genetic susceptibility to type 2 diabetes was first suggested ...
Cited by 25 - Related articles - BL Direct - All 5 versions

A graphical assessment of p-values from sliding window haplotype tests of association to …


RA Mathias, P Gao, JL Goldstein, AF Wilson, … - BMC genetics, 2006 - biomedcentral.com
Past work on asthmatic African American families revealed a strong linkage peak
with modest evidence of association on chromosome 11q. Here, we perform tests of
association for asthma and a panel of 609 SNPs in African American subjects ...
Cited by 18 - Related articles - Cached - All 8 versions

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic …


F Vasseur, D Meyre, P Froguel - Expert Reviews in Molecular Medicine, 2006 - Cambridge Univ Press
Adiponectin, a protein exclusively secreted by adipose tissue but present at low
levels in obesity, is now widely recognised as a key determinant of insulin
sensitivity and of protection against obesity-associated metabolic ...
Cited by 17 - Related articles - All 2 versions


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