JA Todd, NM Walker, JD Cooper, DJ Smyth, K … - Nature genetics, 2007 - pubmedcentral.nih.gov Nat Genet. Author manuscript; available in PMC 2008 July 31. ... 1 Juvenile
Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation
Laboratory, Cambridge Institute for Medical Research, University of ... Cited by 330 - Related articles - BL Direct - All 8 versions
- ►nih.gov LA Criswell, KA Pfeiffer, RF Lum, B Gonzales … - The American Journal of Human Genetics, 2005 - Elsevier Autoimmune disorders constitute a diverse group of phenotypes with overlapping
features and a tendency toward familial aggregation. It is likely that common
underlying genes are involved in these disorders. Until very recently, no ... Cited by 207 - Related articles - All 19 versions
DJ Smyth, JD Cooper, R Bailey, S Field, O … - Nature genetics, 2006 - nature.com 2 Clinic of Diabetes, Institute of Diabetes, Nutrition and Metabolic Diseases
'N.Paulescu', Bucharest 79811, Romania. ... 3 Department of Paediatrics,
University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2XY, UK. Cited by 190 - Related articles - BL Direct - All 6 versions
- ►joslinresearch.org [PDF] H Hakonarson, SFA Grant, JP Bradfield, L … - Nature, 2007 - nature.com Type 1 diabetes (T1D) in children results from autoimmune destruction of
pancreatic beta cells, leading to insufficient production of insulin 1 . A
number of genetic determinants of T1D have already been established through ... Cited by 153 - Related articles - BL Direct - All 7 versions
- ►nih.gov A Vella, JD Cooper, CE Lowe, N Walker, S … - The American Journal of Human Genetics, 2005 - Elsevier Despite hundreds of association studies, few have been consistently replicated
(Dahlman et al. 2002; Hirschhorn et al. 2003; Ioannidis et al. 2003; Lohmueller
et al. 2003). In type 1 diabetes (T1D [MIM 222100]), only four loci have ... Cited by 137 - Related articles - All 6 versions
- ►nih.gov VEH Carlton, X Hu, AP Chokkalingam, SJ … - The American Journal of Human Genetics, 2005 - Elsevier The minor allele of the R620W missense single-nucleotide polymorphism (SNP)
(rs2476601) in the hematopoietic-specific protein tyrosine phosphatase gene,
PTPN22, has been associated with multiple autoimmune diseases, including ... Cited by 108 - Related articles - BL Direct - All 15 versions
- ►oxfordjournals.org YH Lee, YH Rho, SJ Choi, JD Ji, GG Song, SK … - Rheumatology, 2007 - Br Soc Rheumatology Objective. To assess whether combined evidence shows the association between the
protein tyrosine phosphatase non-receptor 22 (PTPN22) C1858T polymorphism and
autoimmune diseases, and to summarize the effect size of the polymorphism ... Cited by 99 - Related articles - BL Direct - All 5 versions
PK Gregersen, HS Lee, F Batliwalla, AB … - Seminars in Immunology, 2006 - Elsevier The 620W allelic variant of the intracellular tyrosine phosphatase, PTPN22, is
associated with a number of different autoimmune disorders, and this provides
direct evidence for common mechanisms underlying many of these diseases. ... Cited by 92 - Related articles - All 2 versions
A Hinks, A Barton, S John, I Bruce, C … - Arthritis Care & Research - interscience.wiley.com The protein tyrosine phosphatase N22 (PTPN22) gene exhibits regulatory
activities for both T cells and B cells. A missense single-nucleotide
polymorphism (SNP) within this gene (rs2476601) has recently been ... Cited by 93 - Related articles - All 3 versions
- ►endojournals.org JM Barker - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Type 1 diabetes (T1D) is associated with autoimmune thyroid disease
(AIT), celiac disease (CD), Addison's disease (AD), and other autoimmune
diseases. These diseases can occur together in defined syndromes with ... Cited by 91 - Related articles - BL Direct - All 6 versions
