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Scholar Results 1 - 10 of about 28 citing Qiu: Hepatic PTP-1B Expression Regulates the Assembly and Secretion of Apolipoprotein B–Contain.... (0.09 sec) 

Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins


TKT Lam, R Gutierrez-Juarez, A Pocai, S … - Nature medicine, 2007 - nature.com
Increased production of very low-density lipoprotein (VLDL) is a critical
feature of the metabolic syndrome. Here we report that a selective increase in
brain glucose lowered circulating triglycerides (TG) through the inhibition ...
Cited by 35 - Related articles - BL Direct - All 4 versions

Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms


AC Rutledge, K Adeli - Nutrition reviews, 2007 - ingentaconnect.com
Emerging evidence suggests that increased dietary consumption of fructose in
Western society may be a potentially important factor in the growing rates of
obesity and the metabolic syndrome. This review will discuss ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model …

- jbc.org
JPF Morand, J Macri, K Adeli - Journal of Biological Chemistry, 2005 - ASBMB
Hepatic insulin resistance and lipoprotein overproduction are common features of
the metabolic syndrome and insulin-resistant states. A fructose-fed,
insulin-resistant hamster model was recently developed to investigate ...
Cited by 21 - Related articles - All 6 versions

Reduction of PTP1B by RNAi upregulates the activity of insulin controlled fatty acid …


J Xu, L Li, Z Qian, J Hong, S Shen, W Huang - Biochemical and biophysical research communications, 2005 - Elsevier
Metabolic deregulation accompanying type II diabetes is characterized by insulin
resistance in peripheral tissues (liver, muscle, and adipose), mediated by
impairments in insulin receptor (IR) signaling. Protein tyrosine ...
Cited by 18 - Related articles - All 6 versions

Consumption of fructose-sweetened beverages for 10 weeks increases postprandial …

- usda.gov [PDF] 
MM Swarbrick, KL Stanhope, SS Elliott, JL … - British Journal of Nutrition, 2008 - Cambridge Univ Press
1 Department of Nutrition, University of California, Davis, CA 95616, USA 2
Department of Molecular Biosciences, School of Veterinary Medicine, University
of California, Davis, CA, USA 3 Department of Atherosclerosis Research, ...
Cited by 15 - Related articles - All 6 versions

Diabetes Altered Gene Expression in Rat Skeletal Muscle Corrected by Oral Administration …

- physiology.org [PDF] 
GR Willsky, LH Chi, Y Liang, DP Gaile, Z Hu, … - Physiological Genomics, 2006 - Am Physiological Soc
Page 1. PG-00196-2005.R1 1 1 Final Accepted Version Diabetes Altered Gene Expression
in Rat Skeletal Muscle Corrected by Oral Administration of Vanadyl Sulfate ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Therapeutic strategies for targeting PTP1B in diabetes


J Montalibet, BP Kennedy - Drug Discovery Today: Therapeutic Strategies, 2005 - Elsevier
Insulin resistance is a hallmark of type 2 diabetes. The protein tyrosine
phosphatase 1B (PTP1B) has been proposed as a novel target whose inhibition
would specifically address insulin resistance. In addition to insulin ...
Cited by 11 - Related articles

How insulin receptor substrate proteins regulate the metabolic capacity of the liver- …

- bentham.org [PDF] 
L Fritsche, C Weigert, HU Haring, R Lehmann - Current medicinal chemistry, 2008 - ingentaconnect.com
Department of Internal Medicine 4, Div. of Clinical Chemistry and
Pathobiochemistry, Central Laboratory, University Hospital Tue- bingen, D-72076
Tuebingen, Germany Abstract: The liver plays a key role in glucose ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of …

- jlr.org
W Qiu, RK Avramoglu, AC Rutledge, J Tsai, K … - The Journal of Lipid Research, 2006 - ASBMB
Glucosamine-induced endoplasmic reticulum (ER) stress was recently shown to
specifically reduce apolipoprotein B-100 (apoB-100) secretion by enhancing the
proteasomal degradation of apoB-100. Here, we examined the mechanisms ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Modeling and informatics in designing anti-diabetic agents


PV Bharatam, DS Patel, L Adane, A Mittal, S … - Current pharmaceutical design, 2007 - ingentaconnect.com
Abstract: Diabetes mellitus is a chronic metabolic disorder, characterized by
glucose overproduction and glucose underutilization. Cur- rent therapy for T2DM
includes drugs, like metformin, glitazones, sulphonyl ureas, etc. Extensive ...
Cited by 7 - Related articles - BL Direct - All 3 versions


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