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Scholar Results 1 - 5 of 5 citing Straub: Massive Augmentation of Stimulated Insulin Secretion Induced by Fatty Acid–Free.... (0.11 sec) 

Life and death decisions of the pancreatic beta-cell: the role of fatty acids


P Newsholme, D Keane, H Welters, N Morgan - Clinical Science, 2007 - submit.clinsci.org
Abbreviations: ACC, acetyl-CoA carboxylase; AMPK, AMP-activated kinase; CPT-1,
carnitine palmitoyltransferase-1; DAG, diacylglycerol; ER, endoplasmic
reticulum; GLP-1, glucagon-like peptide-1; GSIS, glucose-stimulated insulin ...
Cited by 29 - Related articles - Cached - BL Direct - All 8 versions

A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic …

- physiology.org
PO Westermark, JH Kotaleski, A Bjorklund, V … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
The pancreatic -cells respond to an increased glycolytic flux by secreting
insulin. The signal propagation goes via mitochondrial metabolism, which relays
the signal to different routes. One route is an increased ATP production ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation …


D Keane, P Newsholme - Biochemical Society Transactions, 2008 - biochemsoctrans.org
Both stimulatory and detrimental effects of NEFAs (non-esterified fatty acids)
on pancreatic β-cells have been recognized. Acute exposure of the pancreatic
β-cell to high glucose concentrations and/or saturated NEFAs results in a ...
Cited by 3 - Related articles - Cached - All 3 versions

Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty …

- nih.gov
WS Zawalich, KC Zawalich - Metabolism, 2008 - Elsevier
Incubation in 100 μmol/L fatty acid–free bovine serum albumin (FAF-BSA)
significantly amplifies insulin secretion from isolated, perifused rat islets.
When compared with the responses of control islets incubated in 100 μmol/L ...
Cited by 2 - Related articles - All 14 versions

Serum albumin protects from cytokine-induced pancreatic β cell death by a …


C Kiaer, P Thams - Endocrine, 2009 - Springer
Abstract The present study was undertaken to investi- gate the biological
activity of serum albumin when pancreatic b cells were challenged by cytokines
and pro- apoptotic reactive oxygen species like H2O2. Culture of mouse ...
Cited by 1 - Related articles - All 2 versions


 


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