- ►nih.gov H Shi, MV Kokoeva, K Inouye, I Tzameli, H Yin, … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig TLR4 is the receptor for LPS and plays a critical role in innate immunity.
Stimulation of TLR4 activates proinflammatory pathways and induces cytokine
expression in a variety of cell types. Inflammatory pathways are activated ... Cited by 308 - Related articles - BL Direct - All 13 versions
- ►ahajournals.org J Kim, M Montagnani, KK Koh, MJ Quon - Circulation, 2006 - Am Heart Assoc Endothelial dysfunction contributes to cardiovascular diseases, including
hypertension, atherosclerosis, and coronary artery disease, which are also
characterized by insulin resistance. Insulin resistance is a hallmark of ... Cited by 312 - Related articles - All 9 versions
- ►ahajournals.org T Suganami, K Tanimoto-Koyama, J Nishida, M … - Arteriosclerosis, thrombosis, and vascular biology, 2007 - Am Heart Assoc From the Department of Molecular Medicine and Metabolism (TS, KT-K., JN, MI, XY,
YK, YO) and the Center of Excellence Program for Frontier Research on Molecular
Destruction and Reconstitution of Tooth and Bone (YO), Medical Research ... Cited by 95 - Related articles - All 9 versions
- ►diabetesjournals.org XL Wang, L Zhang, K Youker, MX Zhang, J … - Diabetes, 2006 - Am Diabetes Assoc In metabolic syndrome, a systemic deregulation of the insulin pathway leads to a
combined deregulation of insulin-regulated metabolism and cardiovascular
functions. Free fatty acids (FFAs), which are increased in metabolic ... Cited by 48 - Related articles - BL Direct - All 4 versions
E Schleicher, U Friess - Kidney International, 2007 - nature.com Numerous reports on the molecular mechanism of atherogenesis indicate an
increase in oxidative stress, formation of advanced glycoxidation end products
(AGEs), chronic inflammation, and activated cellular response particularly ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org K Staiger, H Staiger, C Weigert, C Haas, HU … - Diabetes, 2006 - Am Diabetes Assoc High nonesterified fatty acid (NEFA) concentrations, as observed in the
metabolic syndrome, trigger apoptosis of human umbilical vein endothelial cells.
Since endothelial apoptosis may contribute to atherothrombosis, we studied ... Cited by 21 - Related articles - BL Direct - All 6 versions
I Aeberli, L Molinari, G Spinas, R Lehmann, … - American Journal of Clinical Nutrition, 2006 - ajcn.org.p.angrylapdog.com Design: In a cross-sectional study of 6–14-y-old normal-weight (n = 33),
overweight (n = 19), and obese (n = 27) Swiss children, nutritional intakes were
assessed from two 24-h dietary recalls and a 1-d dietary record. Percentage ... Cited by 19 - Related articles - BL Direct - All 9 versions
A Mathur, M Marine, D Lu, DA Swartz-Basile, … - HPB: The Official Journal of the International Hepato …, 2007 - pubmedcentral.nih.gov Background. Obesity leads to fat infiltration of multiple organs including the
heart, kidneys, and liver. Under conditions of oxidative stress, fat-derived
cytokines are released locally and result in an inflammatory process and ... Cited by 13 - Related articles - BL Direct - All 7 versions
L Håversen, KN Danielsson, L Fogelstrand, O … - Atherosclerosis, 2009 - Elsevier Increased circulating free fatty acids in subjects with type 2 diabetes may
contribute to activation of macrophages, and thus the development of
atherosclerosis. In this study, we investigated the effect of the saturated ... Cited by 10 - Related articles - All 26 versions
RL Bradley, FFM Fisher, E Maratos-Flier - Obesity, 2008 - nature.com Obesity correlates with increased production of adipocyte-derived cytokines,
which may contribute to a chronic subclinical inflammation seen in obese
individuals. This study evaluated the ability of specific fatty acids to ... Cited by 8 - Related articles - All 2 versions
