- ►pnas.org K Komeima, BS Rogers, L Lu, PA … - Proceedings of the …, 2006 - National Acad Sciences Retinitis pigmentosa (RP) is a label for a group of diseases caused by a large number of mutations
that result in rod photoreceptor cell death followed by gradual death of cones. The mechanism of
cone cell death is uncertain. Rods ... Cited by 54 - Related articles - BL Direct - All 11 versions
RA Kowluru, V Kowluru, Y Xiong, YS Ho - Free Radical Biology and Medicine, 2006 - Elsevier The retina experiences mitochondrial dysfunction in diabetes, superoxide levels are elevated, and
mitochondrial superoxide dismutase (MnSOD) activity is decreased. Inhibition of superoxide
accumulation in diabetes prevents ... Cited by 40 - Related articles - All 5 versions
RA Kowluru - Antioxidants & Redox Signaling, 2005 - liebertonline.com R ETINOPATHY , A PROGRESSIVE DISEASE , is one of the most debilitating complications of diabetes. It
is the leading cause of acquired blindness among young adults in developed countries. Animal models
have shown that hyperglycemia- ... Cited by 39 - Related articles - BL Direct - All 4 versions
RA Kowluru, M Kanwar - Nutrition & Metabolism, 2007 - biomedcentral.com Page 1 of 8 (page number not for citation purposes) ... Effects of curcumin on retinal oxidative
stress and inflammation in ... Address: Kresge Eye Institute, Wayne State University, Detroit, MI,
USA Email: Renu A Kowluru* - ... Cited by 35 - Related articles - View as HTML - All 13 versions
- ►iovs.org RA Kowluru, L Atasi, YS Ho - Investigative ophthalmology & visual science, 2006 - ARVO PURPOSE. Apoptosis of retinal capillary cells is an early event in the pathogenesis of retinopathy
in diabetes, and oxidative stress has been linked to accelerated apoptosis of retinal capillary
cells. Mitochondria are the major ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►iovs.org RA Kowluru, S Odenbach - Investigative ophthalmology & visual science, 2004 - ARVO RESULTS. The number of TUNEL-positive capillary cells in the retinal microvessels obtained from
normal rats that received intravitreal injection of IL-1ß was increased by more than threefold and
that of acellular capillaries by ... Cited by 33 - Related articles - BL Direct - All 3 versions
TS Kern - Exp Diabetes Res, 2007 - hindawi.com Diabetes causes metabolic and physiologic abnormalities in the retina, and these changes suggest a
role for inflammation in the development of diabetic retinopathy. These changes include upregulation
of iNOS, COX-2, ICAM-1, caspase 1, ... Cited by 34 - Related articles - View as HTML - All 12 versions
- ►pubget.com [PDF] J Lin, A Bierhaus, P Bugert, N Dietrich, Y Feng, F Vom … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1089–1096 DOI 10.1007/s00125-006-0174-y ARTICLE J. Lin . A.
Bierhaus . P. Bugert . N. Dietrich . Y. Feng . F. vom Hagen . P. Nawroth . M. Brownlee .
H.-P. Hammes Effect of R-(+)-α-lipoic acid on experimental diabetic retinopathy ... Cited by 28 - Related articles - BL Direct - All 4 versions
RA Kowluru, PS Chan - Exp Diabetes Res, 2007 - downloads.hindawi.com Oxygen metabolism is essential for sustaining aerobic life, and normal cellular homeostasis works on
a fine balance between the formation and elimination of reactive oxygen species (ROS). Oxidative
stress, a cytopathic consequence of ... Cited by 30 - Related articles - View as HTML - All 13 versions
L Li, G Renier - Metabolism, 2006 - Elsevier Increasing evidence indicates that advanced glycation end products (AGEs) promote retinal
alterations through oxidative stress. However, the pathways involved in AGE-induced generation of
reactive oxygen species (ROS) in ... Cited by 23 - Related articles - All 6 versions
