N Das Evcimen, GL King - Pharmacological research, 2007 - Elsevier Diabetes mellitus is a chronic disease caused by inherited and/or acquired
deficiency in production of insulin by the pancreas, and by resistance to
insulin's effects. Such a deficiency results in increased concentrations of ... Cited by 63 - Related articles - All 4 versions
- ►nih.gov O Ilnytska, VV Lyzogubov, MJ Stevens, VR … - Diabetes, 2006 - Am Diabetes Assoc Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental
mechanism in the pathogenesis of diabetes complications including diabetic
neuropathy. This study evaluated the role of PARP in diabetic sensory ... Cited by 26 - Related articles - BL Direct - All 10 versions
K Sugimoto, M Yasujima, S Yagihashi - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: Diabetic neuropathy is the commonest form of peripheral neuropathy in
the developed countries of the world. In diabetic pa- tients, the presence of
peripheral neuropathy increases their risks for developing foot ulceration ... Cited by 22 - Related articles - BL Direct - All 3 versions
- ►physiology.org IG Obrosova, VR Drel, CL Oltman, N Mashtalir … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Evidence for important roles of the highly reactive oxidant peroxynitrite in
diabetic complications is emerging. We evaluated the role of peroxynitrite in
early peripheral neuropathy and vascular dysfunction in STZ-diabetic rats. ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►shouxi.net C Demiot, M Tartas, B Fromy, P Abraham, JL … - Diabetes, 2006 - Am Diabetes Assoc Pressure-induced vasodilation, a neurovascular mechanism relying on the
interaction between mechanosensitive C-fibers and vessels, allows skin blood
flow to increase in response to locally nonnociceptive applied pressure ... Cited by 10 - Related articles - BL Direct - All 5 versions
C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ... Cited by 11 - Related articles - All 2 versions
- ►nih.gov DY Liang, X Shi, X Li, J Li, JD Clark - Behavioural brain research, 2007 - Elsevier Adaptations to the chronic administration of opioids reduce the utility of these
drugs in treating pain and support addiction. Recent genetics-based approaches
have implicated the β2 adrenergic receptor (β2-AR) in controlling some of ... Cited by 8 - Related articles - All 5 versions
- ►cjb.net M Chattopadhyay, M Mata, DJ Fink - Journal of Neuroscience, 2008 - neuro.cjb.net The Na V 1.7 tetrodotoxin-sensitive voltage-gated sodium channel isoform plays a
critical role in nociception. In rodent models of diabetic neuropathy, increased
Na V 1.7 in dorsal root ganglia (DRG) neurons correlates with the emergence ... Cited by 7 - Related articles - All 4 versions
Y Kuzumoto, S Kusunoki, N Kato, M Kihara, … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Fidarestat, an aldose reductase inhibitor (ARI), has
been reported to improve clinical symptoms and nerve conduction deficits in
human diabetic neuropathy. We evaluated the dose-dependency and some of the ... Cited by 9 - Related articles - BL Direct - All 5 versions
SI Yamagishi, S Ogasawara, H Mizukami, N … - Journal of neurochemistry, 2008 - pt.wkhealth.com Pioglitazone, one of thiazolidinediones, a peroxisome proliferator-activated
receptor (PPAR)-γ ligand, is known to have beneficial effects on macrovascular
complications in diabetes, but the effect on diabetic neuropathy is not ... Cited by 6 - Related articles - BL Direct - All 5 versions
