- ►diabetesjournals.org P Achenbach, E Bonifacio, K Koczwara, AG … - Diabetes, 2005 - Am Diabetes Assoc The natural history of autoimmune type 1 diabetes in children is associated with
the appearance of islet autoantibodies early in life, which is influenced by
genetic and environmental factors. Once islet autoantibodies have ... Cited by 37 - Related articles - BL Direct - All 9 versions
JMM Howson, BJ Barratt, JA Todd, HJ Cordell - Genetic epidemiology, 2005 - interscience.wiley.com We compared different ascertainment schemes for genetic association analysis:
affected sib-pairs (ASPs), case-parent trios, and unrelated cases and controls.
We found, with empirical type 1 diabetes data at four known disease loci, ... Cited by 23 - Related articles - BL Direct - All 3 versions
R Hermann, AP Laine, R Veijola, T Vahlberg, S … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The aim of this study was to explore the contribution
of genetic factors to the emer- gence of beta-cell-specific humoral
autoimmunity. Subjects and methods: We analysed the effect of HLA class II, ... Cited by 18 - Related articles - BL Direct - All 4 versions
P Achenbach, E Bonifacio, AG Ziegler - Current Diabetes Reports, 2005 - Springer Introduction Accurate estimation of the risk for developing type 1 diabetes
mellitus (T1DM) is important for the identification of indi- viduals who may
benefit from inclusion in interventional trials aiming to prevent the onset ... Cited by 17 - Related articles - All 2 versions
JAL Armour - … Research-Fundamental and Molecular Mechanisms of …, 2006 - Elsevier Recent excitement over SNPs has tended to obscure the real advantages of
studying tandemly repeated loci. In this commentary, I make the case for
studying tandem repeats, concentrating on two major arguments. Firstly, ... Cited by 17 - Related articles - All 4 versions
- ►shouxi.net T Tuomi - Diabetes, 2005 - Am Diabetes Assoc Type 1 and type 2 diabetes frequently co-occur in the same families, suggesting
common genetic susceptibility. Such mixed family history is associated with an
intermediate phenotype of diabetes: insulin resistance and cardiovascular ... Cited by 16 - Related articles - BL Direct - All 8 versions
K Haller, K Kisand, H Pisarev, L Salur, T … - Tissue Antigens, 2007 - interscience.wiley.com Recent research has underlined the need to explore pathogenic, genetic and
clinical spectrum of adult onset autoimmune diabetes, also known as latent
autoimmune diabetes in adults (LADA). We aimed to investigate whether ... Cited by 11 - Related articles - All 3 versions
- ►nih.gov M Bjørnvold, DE Undlien, G Joner, K Dahl- … - Diabetologia, 2008 - Springer Abstract Background/hypothesis HLA, INS, PTPN22 and CTLA4 are considered to be
confirmed type 1 diabetes susceptibil- ity genes. HLA, PTPN22 and CTLA4 are
known to be involved in immune regulation. Few studies have system- Cited by 8 - Related articles - BL Direct - All 6 versions
MG Marrosu, R Murru, G Costa, MC Melis, M … - BMC genetics, 2007 - biomedcentral.com Multiple sclerosis (MS) is consistently associated with particular HLA-DRB1-DQB1
haplotypes. However, existing evidence suggests that variation at these loci
does not entirely explain association of the HLA region with the disease. ... Cited by 4 - Related articles - Cached - All 8 versions
O Raha, S Chowdhury, S Dasgupta, P … - International Journal of Diabetes in Developing …, 2009 - ijddc.com Type 1 diabetes is a multifactorial disease with an early age of onset, in which
the insulin producing β cell of the pancreas are destroyed because of
autoimmunity. It is the second most common chronic disease in children and ... Related articles - Cached - All 2 versions
