- ►diabetesjournals.org W Winckler, MN Weedon, RR Graham, SA … - Diabetes, 2007 - Am Diabetes Assoc An important question in human genetics is the extent to which genes causing
monogenic forms of disease harbor common variants that may contribute to the
more typical form of that disease. We aimed to comprehensively evaluate the ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org H Freeman, RD Cox - Human molecular genetics, 2006 - Oxford Univ Press Diabetes is one of the most challenging health problems of the 21st century with
an alarming increase in the prevalence of type-2 diabetes mellitus (T2DM) and
associated conditions such as hypertension, dyslipidemias and obesity. T2DM ... Cited by 48 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org [PDF] E Rampersaud, CM Damcott, M Fu, H Shen, P … - Diabetes, 2007 - Am Diabetes Assoc Evadnie Rampersaud 1 , Coleen M. Damcott 1 , Mao Fu 1 , Haiqing Shen 1 , Patrick
McArdle 1 , ... Xiaolian Shi 1 , John Shelton 1 , Jing Yin 1 ,Christy Y. Chang
1 ,Sandra H. Ott 1 , Li Zhang 1 , ... Yiju Zhao 1 , Braxton D. Mitchell 1 ... Cited by 44 - Related articles - BL Direct - All 6 versions
- ►shouxi.net LL Bonnycastle, CJ Willer, KN Conneely, AU … - Diabetes, 2006 - Am Diabetes Assoc Prior reports have suggested that variants in the genes for maturity-onset
diabetes of the young (MODY) may confer susceptibility to type 2 diabetes, but
results have been conflicting and coverage of the MODY genes has been ... Cited by 40 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org YL Muller, AM Infante, RL Hanson, L Love- … - Diabetes, 2005 - Am Diabetes Assoc Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α
(HNF4α) gene are associated with type 2 diabetes in Finns and Ashkenazi Jews.
Previous studies in both populations have reported linkage to type 2 ... Cited by 37 - Related articles - BL Direct - All 6 versions
SK Das, SC Elbein - Cellscience, 2006 - pubmedcentral.nih.gov Type 2 Diabetes results from a complex physiologic process that includes the
pancreatic beta cells, peripheral glucose uptake in muscle, the secretion of
multiple cytokines and hormone-like molecules from adipocytes, hepatic ... Cited by 25 - Related articles - All 3 versions
- ►diabetesjournals.org K Hara, M Horikoshi, H Kitazato, C Ito, M … - Diabetes, 2006 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is a transcription factor known as a key
molecule in the development and functions of the β-cells. In a previously
performed genome-wide scan of Japanese type 2 diabetic sibpairs, we ... Cited by 25 - Related articles - BL Direct - All 5 versions
E Suviolahti, HE Lilja, P Pajukanta - Annals of Medicine, 2006 - informahealthcare.com Familial combined hyperlipidemia (FCHL) constitutes a substantial risk factor
for atherosclerosis since it is observed in about 20% of coronary heart disease
(CHD) patients under 60 years. FCHL, characterized by elevated levels of ... Cited by 22 - Related articles - BL Direct - All 7 versions
H Ræder, L Bjørkhaug, S Johansson, K … - Diabetes, 2006 - Am Diabetes Assoc Variants in hepatocyte nuclear factor (HNF)-4α cause maturity-onset diabetes of
the young, type 1 (MODY1) and may also be risk factors for type 2 diabetes. We
sequenced the HNF4A gene of 95 MODY3-negative probands from the Norwegian ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org D Weissglas-Volkov, A Huertas-Vazquez, E … - Diabetes, 2006 - Am Diabetes Assoc Hepatic nuclear factor-4α (HNF-4α), a transcription factor involved in the
regulation of serum lipid and glucose levels, has recently been associated with
type 2 diabetes. The HNF-4α gene (HNF4A) resides on chromosome ... Cited by 18 - Related articles - BL Direct - All 7 versions
