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Scholar Results 1 - 10 of about 20 citing Gosmain: Sterol regulatory element-binding protein-1 mediates the effect of insulin on hexokinase.... (0.09 sec) 

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on …

- jbc.org
R Dentin, JP Pegorier, F Benhamed, F … - Journal of Biological Chemistry, 2004 - ASBMB
Hepatic glucokinase (GK) catalyzes the phosphorylation of glucose to glucose
6-phosphate (G6P), a step which is essential for glucose metabolism in liver as
well as for the induction of glycolytic and lipogenic genes. The sterol ...
Cited by 132 - Related articles - BL Direct - All 6 versions

Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during …

- jlr.org
Y Gosmain, N Dif, V Berbe, E Loizon, J … - The Journal of Lipid Research, 2005 - ASBMB
The sterol regulatory element binding protein 1 (SREBP-1) is regarded as a major
factor involved in the nutritional regulation of lipogenesis. The aim of the
present work was to demonstrate its involvement in the response of key ...
Cited by 36 - Related articles - All 4 versions

Fatty acids and the metabolic syndrome


HM Roche - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press
The metabolic syndrome is a very common condition, characterised by insulin
resistance, dyslipidaemia, abdominal obesity and hypertension, that is
associated with a high risk of type 2 diabetes mellitus (T2DM) and CVD. ...
Cited by 25 - Related articles - All 8 versions

Differential regulation of metabolic genes in skeletal muscle during starvation and …


K Tsintzas, K Jewell, M Kamran, D Laithwaite, … - The Journal of Physiology, 2006 - Physiological Soc
This study investigated the molecular alterations underlying the physiological
adaptations to starvation and refeeding in human skeletal muscle. Forty-eight
hours' starvation reduced whole-body insulin sensitivity by 42% and ...
Cited by 21 - Related articles - BL Direct - All 7 versions

Dietary lipids and gene expression


H Roche - Biochemical Society Transactions, 2004 - bst.portlandpress.com
Nutrition is a key environmental factor that is particularly involved in the
pathogenesis and progression of several polygenic, diet-related diseases.
Nutrigenomics refers to the interaction between nutrition and the human ...
Cited by 20 - Related articles - Cached - BL Direct - All 12 versions

Activation of liver X receptors promotes lipid accumulation but does not alter insulin action …


D Cozzone, C Debard, N Dif, N Ricard, E Disse … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 990–999 DOI 10.1007/s00125-006-0140-8 ARTICLE D.
Cozzone . C. Debard . N. Dif . N. Ricard . E. Disse . J. Vouillarmet . ...
Cited by 19 - Related articles - BL Direct - All 2 versions

Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter …


N Dif, V Euthine, E Gonnet, M Laville, H Vidal, … - Biochemical Journal, 2006 - pubmedcentral.nih.gov
In the present study, we aimed to decipher the mechanisms involved in the
transcriptional effect of insulin on the SREBP-1c specific promoter of the human
srebf-1 gene. Using luciferase reporter gene constructs in HEK-293 cells ...
Cited by 14 - Related articles - BL Direct - All 8 versions

Control of muscle bioenergetic gene expression: implications for allometric scaling …

- biologists.org
CD Moyes, CMR LeMoine - Journal of Experimental Biology, 2005 - jeb.biologists.org
Muscle metabolic properties vary with body size, with larger animals relying
relatively less on oxidative metabolism as a result of lower specific activities
of mitochondrial enzymes and greater specific activities of glycolytic ...
Cited by 13 - Related articles - All 6 versions

Adipose Tissue Integrity as a Prerequisite for Systemic Energy Balance


SI Anghel, E Bedu, CD Vivier, P Descombes, … - Journal of Biological Chemistry, 2007 - ASBMB
Peroxisome proliferator-activated receptor γ (PPARγ) is an essential regulator
of adipocyte differentiation, maintenance, and survival. Deregulations of its
functions are associated with metabolic diseases. We show here that ...
Cited by 7 - Related articles - All 5 versions

Expression of genes regulating malonyl-CoA in human skeletal muscle


C Pender, AR Trentadue, WJ Pories, GL … - Journal of cellular biochemistry, 2006 - interscience.wiley.com
In humans and animal models, increased intramuscular lipid (IML) stores have
been implicated in insulin resistance. Malonyl-CoA plays a critical role in
cellular lipid metabolism both by serving as a precursor in the synthesis ...
Cited by 6 - Related articles - BL Direct - All 5 versions


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