- ►endojournals.org EE Kershaw, JS Flier - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Adipose tissue is a complex, essential, and highly active metabolic and endocrine organ. Besides
adipocytes, adipose tissue contains connective tissue matrix, nerve tissue, stromovascular
cells, and immune cells. Together these components function as an integrated unit. ... Cited by 1086 - Related articles - BL Direct - All 8 versions
T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel, G … - Obesity, 2006 - pbrc.edu Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN
WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2005 update. Obesity. 2006;14: ... Cited by 335 - Related articles - View as HTML - All 6 versions
L Perusse, T Rankinen, A Zuberi, YC Chagnon, … - Obesity …, 2005 - informatik.hu-berlin.de Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND
CLAUDE BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ... Cited by 210 - Related articles - View as HTML - All 6 versions
SE Shoelson, L Herrero, A Naaz - Gastroenterology, 2007 - Elsevier Weight gain and obesity are major risk factors for conditions and diseases ranging from insulin
resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of nonalcoholic fatty
liver disease. A chronic, subacute state of inflammation often accompanies the ... Cited by 149 - Related articles - All 23 versions
H Kolb, T Mandrup-Poulsen - Diabetologia, 2005 - Springer Abstract Subclinical, low-grade systemic inflammation has been observed in patients with type
2 diabetes and in those at increased risk of the disease. This may be more than an
epiphenomenon. Alleles of genes encoding immune/ inflammatory mediators are ... Cited by 118 - Related articles - BL Direct - All 5 versions
SA Summers - Progress in Lipid Research, 2006 - Elsevier Obesity predisposes individuals to the development of insulin resistance in skeletal muscle and
the liver, and researchers have recently proposed two mechanisms by which excess adiposity
antagonizes insulin action in peripheral tissues. First, when adipocytes exceed their ... Cited by 114 - Related articles - All 3 versions
- ►asnjournals.org SP Bagby - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol Metabolic syndrome, originally described in 1988 as "syndrome X" by Reaven et al. (1), has evolved
in our collective thinking from a vague association of common chronic disease states to a formally
defined cluster of clinical traits with adverse impact on cardiovascular risk (2). The cause ... Cited by 111 - Related articles - BL Direct - All 4 versions
MC Alessi, I Juhan-Vague - Arteriosclerosis, thrombosis, and vascular …, 2006 - Am Heart Assoc The link between plasminogen activator inhibitor (PAI)-1 and the metabolic syndrome with obesity
was established many years ago. Increased PAI-1 level can be now considered a true component
of the syndrome. The metabolic syndrome is associated with an increased risk of ... Cited by 106 - Related articles - All 9 versions
HR Lijnen - Journal of Thrombosis and Haemostasis, 2005 - geno-type.com Summary. Plasminogen activator inhibitor-1 (PAI-1), a 45-kDa serine proteinase inhibitor with
reactive site peptide bond Arg345-Met346, is the main physiological plasminogen activator
inhibitor. It occurs in human plasma at an antigen concentration of about 20 ng mL )1 . ... Cited by 98 - Related articles - View as HTML - All 7 versions
H Hauner - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Obesity is characterized by an expanded adipose tissue mass. Recent data suggest that adipose
tissue is a multi-functional organ rather than simply a passive storage site for excess energy.
It has been clearly demonstrated that human adipose tissue produces a variety of ... Cited by 97 - Related articles - All 6 versions
