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Scholar Results 1 - 10 of about 56 citing Nikolic: Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic.... (0.10 sec) 

[PDF] Treatment of severe autoimmune disease by stem-cell transplantation


M Sykes, B Nikolic - Nature, 2005 - direct-ms.org
Transplantation of haematopoietic stem cells — cells capable of self renewing
and reconstituting all types of blood cell — can treat numerous lethal
diseases, including leukaemias and lymphomas. It may now be applicable for ...
Cited by 101 - Related articles - View as HTML - All 6 versions

Tolerance induction in clinical transplantation


T Fehr, M Sykes - Transplant immunology, 2004 - Elsevier
Introduction of modern immunosuppressive agents has led to great success of
allotransplantation in humans, and survival rates for all solid organs have been
dramatically improved. However, a constant proportion of organs is lost ...
Cited by 76 - Related articles - All 3 versions

Chimerism as a tool to induce clinical transplantation tolerance


F Claas - Current opinion in immunology, 2004 - Elsevier
The induction of donor-specific transplantation tolerance would be the obvious
solution to all of these complications. Recent experimental and clinical
evidence suggests that transplantation tolerance might become an achievable ...
Cited by 36 - Related articles - All 3 versions

Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in …

- hematologylibrary.org
Y Liang, T Huang, C Zhang, I Todorov, M … - Blood, 2005 - bloodjournal.hematologylibrary.org
Prevention of autoimmune diabetes and induction of islet transplantation
tolerance in nonobese diabetic (NOD) mice can be reached by induction of mixed
chimerism via bone marrow transplantation (BMT), but this procedure ...
Cited by 34 - Related articles - All 6 versions

Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes

- ualberta.ca [PDF] 
AN Balamurugan, R Bottino, N Giannoukakis … - Pancreas, 2006 - journals.lww.com
Abstract: Pancreatic islet cell transplantation is an attractive treatment of
type 1 diabetes (T1D). The success enhanced by the Edmonton protocol has
fostered phenomenal progress in the field of clinical islet transplantation ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Mesenchymal Stem Cells Facilitate Induction of Mixed Chimerism and Islet Allograft …


S Itakura, S Asari, J Rawson, T Ito, CP Liu, N … - Transplantation, 2006 - journals.lww.com
Abstract# 352 MESENCHYMAL STEM CELLS FACILITATE INDUCTION OF MIXED CHIMERISM AND
ISLET ALLOGRAFT TOLERANCE WITHOUT GVHD IN THE RAT. Shin Itakura,1,3 Sadaki
Asari,1 Jeffrey Rawson,1 Taihei Ito,1 Chih-Pin Liu,2 Nobuo Sasaki,3 Ivan ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Animal models have little to teach us about Type 1 diabetes: 2. In opposition to this proposal

- vpro.nl [PDF] 
EH Leiter, M Von Herrath - Diabetologia, 2004 - Springer
The contrarians have to agree with their opponents that animal models in
general, and rodent models of Type 1 diabetes in particular, are imperfect
reflections of human disease [1]. This is the inevitable conse- quence of ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Of mice and men: use of animal models to identify possible interventions for the prevention …

- pasteur.ac.ir [PDF] 
DV Serreze, YG Chen - Trends in immunology, 2005 - Elsevier
Also within this special issue of Trends in Immunology, Lernmark and Agardh
raise the daunting question of what hurdles must be overcome to meet the
clinical challenge of developing antigen-based immunotherapies capable of ...
Cited by 13 - Related articles - All 6 versions

Combined islet and hematopoietic stem cell allotransplantation: a clinical pilot trial to …

- prsjournal.net
D Mineo, C Ricordi, X Xu, A Pileggi, R Garcia … - American Journal of Transplantation, 2008 - prsjournal.net
To prevent graft rejection and avoid immunosuppression-related side-effects, we
attempted to induce recipient chimerism and graft tolerance in islet
transplantation by donor CD34+hematopoietic stem cell (HSC) infusion. Six ...
Cited by 11 - Related articles - Cached - BL Direct - All 6 versions

Elimination of insulitis and augmentation of islet β cell regeneration via induction of …


C Zhang, I Todorov, CL Lin, M Atkinson, F … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from
autoreactive T cell destruction of insulin-producing β cells. Cure of type 1
diabetes may require both reversal of autoimmunity and regeneration of β ...
Cited by 11 - Related articles - BL Direct - All 9 versions


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