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Scholar Results 1 - 10 of about 42 citing Mitchell: Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic β-cell Ca2+.... (0.16 sec) 

Microdomains of intracellular Ca2+: molecular determinants and functional …

- physiology.org
R Rizzuto, T Pozzan - Physiological reviews, 2006 - Am Physiological Soc
Calcium ions are ubiquitous and versatile signaling molecules, capable of decoding a variety
of extracellular stimuli (hormones, neurotransmitters, growth factors, etc.) into markedly different
intracellular actions, ranging from contraction to secretion, from proliferation to cell death. ...
Cited by 248 - Related articles - BL Direct - All 5 versions

Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin …

- diabetesjournals.org
JC Henquin - Diabetes, 2004 - Am Diabetes Assoc
Physiologically, insulin secretion is subject to a dual, hierarchal control by triggering and amplifying
pathways. By closing ATP-sensitive K + channels (K ATP channels) in the plasma
membrane, glucose and other metabolized nutrients depolarize β-cells, stimulate Ca 2+ ...
Cited by 37 - Related articles - BL Direct - All 4 versions

A direct interaction between Cdc42 and vesicle-associated membrane protein 2 …

- jbc.org
AK Nevins, DC Thurmond - Journal of Biological Chemistry, 2005 - ASBMB
In pancreatic beta cells, insulin granule exocytosis is regulated by SNARE (soluble
N-ethylmaleimide-sensitive factor attachment protein receptor protein (SNAP) receptor)
proteins, and this is coupled to cortical F-actin reorganization via the Rho family GTPase ...
Cited by 37 - Related articles - All 5 versions

The Ca2+/Mn2+ pumps in the Golgi apparatus

- ulb.ac.be [PDF] 
K Van Baelen, L Dode, J Vanoevelen, G Callewaert … - BBA-Molecular Cell …, 2004 - Elsevier
Recent evidence highlights the functional importance of the Golgi apparatus as an agonist-sensitive
intracellular Ca 2+ store. Besides Ca 2+ -release channels and Ca 2+ -binding proteins, the
Golgi complex contains Ca 2+ -uptake mechanisms consisting of the well-known sarco/ ...
Cited by 34 - Related articles - All 6 versions

Involvement of Per–Arnt–Sim (PAS) kinase in the stimulation of preproinsulin and …


G da Silva Xavier, J Rutter, GA … - Proceedings of the …, 2004 - National Acad Sciences
Per–Arnt–Sim (PAS) domain-containing kinases are common in prokaryotes, but a mammalian
counterpart has only recently been described. Although the PAS domain of the mammalian PAS
kinase (PASK) is closely related to the bacterial oxygen sensor FixL, it is unclear whether ...
Cited by 26 - Related articles - BL Direct - All 11 versions

SPCA1 pumps and Hailey–Hailey disease


L Missiaen, L Raeymaekers, L Dode, J Vanoevelen … - … and Biophysical Research …, 2004 - Elsevier
Both the endoplasmic reticulum and the Golgi apparatus are agonist-sensitive intracellular Ca
2+ stores. The Golgi apparatus has Ca 2+ -release channels and a Ca 2+ -uptake mechanism
consisting of sarco(endo)plasmic-reticulum Ca 2+ -ATPases (SERCA) and secretory- ...
Cited by 25 - Related articles - All 6 versions

The secretory pathway Ca2+/Mn2+-ATPase 2 is a Golgi-localized pump with high …


J Vanoevelen, L Dode, K Van Baelen, RJ … - Journal of Biological …, 2005 - ASBMB
Accumulation of Ca 2+ into the Golgi apparatus is mediated by sarco(endo)plasmic reticulum
Ca 2+ -ATPases (SERCAs) and by secretory pathway Ca 2+ -ATPases (SPCAs). Mammals and
birds express in addition to the housekeeping SPCA1 (human gene name ATP2C1, ...
Cited by 24 - Related articles - All 6 versions

Ca2+ microdomains and the control of insulin secretion


GA Rutter, T Tsuboi, MA Ravier - Cell Calcium, 2006 - Elsevier
Nutrient-induced increases in intracellular free Ca 2+ concentrations are the key trigger for insulin
release from pancreatic islet β-cells. These Ca 2+ changes are tightly regulated temporally, occurring
as Ca 2+ influx-dependent baseline oscillations. We explore here the concept that locally ...
Cited by 22 - Related articles - All 4 versions

A dynamic pool of calcium in catecholamine storage vesicles: exploration in living …

- jbc.org
NR Mahapatra, M Mahata, PP Hazra, PM … - Journal of Biological …, 2004 - ASBMB
Chromaffin vesicles contain very high concentration of Ca 2+ ( 20–40 mM total), compared with
100 nM in the cytosol. Aequorin, a jellyfish photoprotein with Ca 2+ -dependent
luminescence, measures [Ca 2+ ] in specific subcellular compartments wherein proteins ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a …


A Varadi, A Grant, M McCormack, T Nicolson, M … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 1567–1577 DOI 10.1007/s00125-006-0257-9
ARTICLE A. Varadi . A. Grant . M. McCormack . T. Nicolson . M. Magistri . KJ Mitchell .
AP Halestrap . H. Yuan . B. Schwappach . GA Rutter Intracellular ...
Cited by 18 - Related articles - BL Direct - All 4 versions


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