H Ichiia, L Inverardia, A Pileggia, RD … - American Journal of …, 2005 - diabetesresearch.org American Journal of Transplantation 2005; 5: 1635–1645 Blackwell Munksgaard ... Copyright
C Blackwell Munksgaard 2005 doi: 10.1111/j.1600-6143.2005.00913.x ... A Novel Method for
the Assessment of Cellular ... Hirohito Ichiia,c, Luca Inverardia, Antonello Pileggia, R. ... Cited by 75 - Related articles - View as HTML - All 5 versions
- ►diabetesjournals.org WC Ladiges, SE Knoblaugh, JF Morton, MJ Korth, BL … - Diabetes, 2005 - Am Diabetes Assoc The endoplasmic reticulum (ER) transmits apoptotic signals in the pancreas during ER
stress, implicating ER stress–mediated apoptosis in the development of diabetes. P58 IPK
(DNAJC3) is induced during ER stress and functions as a negative feedback component ... Cited by 63 - Related articles - All 6 versions
M Goto, J Holgersson, M Kumagai- … - American Journal of …, 2006 - interscience.wiley.com The current standard assays for islet product release criteria are unable to predict the outcome
after clinical islet transplantation. Therefore, establishment of reliable and rapid assays enabling
pre-transplantation prediction of islet potency is warranted. In the present study, we have ... Cited by 33 - Related articles - BL Direct - All 4 versions
IR Sweet, M Gilbert, R Jensen, O Sabek, DW Fraga, … - Transplantation, 2005 - journals.lww.com Amajor impediment to the optimization of islet isolation procedures is the lack of methods that
adequately assess the quality of islets (1, 2). An in vitro method of assessing human islets prior
to transplantation could prevent the trans- plantation of islets with little chance of efficacy. ... Cited by 17 - Related articles - All 6 versions
KK Papas, A Pisania, H Wu, GC Weir, … - Biotechnology and …, 2007 - interscience.wiley.com Improvements in pancreatic islet transplantation for treatment of diabetes are hindered by the
absence of meaningful islet quality assessment methods. Oxygen consumption rate (OCR) has
previously been used to assess the quality of organs and primary tissue for ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►physiology.org LE Fridlyand, L Ma, LH Philipson - American Journal of …, 2005 - Am Physiological Soc Glucose metabolism stimulates insulin secretion in pancreatic -cells. A consequence of metabolism
is an increase in the ratio of ATP to ADP ([ATP]/[ADP]) that contributes to depolarization of the
plasma membrane via inhibition of ATP-sensitive K + (K ATP ) channels. The subsequent ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org IR Sweet, M Gilbert - Diabetes, 2006 - Am Diabetes Assoc In brain, muscle, and pancreatic islets, depolarization induces an increase in respiration, which
is dependent on calcium influx. The goal of this study was to assess the quantitative significance
of this effect in islets relative to glucose-stimulated ATP turnover, to examine the ... Cited by 10 - Related articles - BL Direct - All 6 versions
G Leibowitz, MZ Khaldi, A Shauer, M Parnes, AI … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1549–1559 DOI 10.1007/s00125-005-1811-6 ARTICLE G.
Leibowitz . MZ Khaldi . A. Shauer . M. Parnes . AI Oprescu . E. Cerasi . J.-C. Jonas . N. Kaiser
Mitochondrial regulation of insulin production in rat pancreatic islets ... Cited by 9 - Related articles - BL Direct - All 4 versions
C Affourtit, MD Brand - Biochemical Journal, 2006 - pubmedcentral.nih.gov Pancreatic beta cells respond to rising blood glucose concen- trations by increasing their oxidative
metabolism, which leads to an increased ATP/ADP ratio, closure of KATP channels, depolar-
ization of the plasma membrane potential, influx of calcium and the eventual secretion of ... Cited by 8 - Related articles - BL Direct - All 10 versions
