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Scholar Results 1 - 10 of about 54 citing Steele: Insulin secretion in type 1 diabetes. (0.10 sec) 

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

- nih.gov
KI Rother, DM Harlan - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
Worldwide, more than 750 individuals with type 1 diabetes mellitus (T1DM) have
received allogeneic islet transplants since 1974, in an effort to cure their
chronic condition. Though this is still a small number (especially when ...
Cited by 103 - Related articles - BL Direct - All 11 versions

Natural history of β-cell function in type 1 diabetes

- diabetesjournals.org
NA Sherry, EB Tsai, KC Herold - Diabetes, 2005 - Am Diabetes Assoc
Despite extensive and ongoing investigations of the immune mechanisms of
autoimmune diabetes in humans and animal models, there is much less information
about the natural history of insulin secretion before and after the ...
Cited by 36 - Related articles - BL Direct - All 6 versions

The rise and fall of insulin secretion in type 1 diabetes mellitus


EB Tsai, NA Sherry, JP Palmer, KC Herold - Diabetologia, 2006 - Springer
Abstract An understanding of the natural history of beta cell responses is an
essential prerequisite for interventional studies designed to prevent or treat
type 1 diabetes. Here we review published data on changes in insulin ...
Cited by 32 - Related articles - BL Direct - All 3 versions

ADA Outstanding Scientific Achievement Lecture 2004

- daegu.ac.kr [PDF] 
MA Atkinson - Diabetes, 2005 - Am Diabetes Assoc
Thirty years ago, a convergence of investigational ob- servations lead to the
now widely accepted notion that type 1 diabetes results from an autoimmune
destruction of insulin-producing -cells in subjects genetically pre- ...
Cited by 28 - Related articles - All 3 versions

Visualizing pancreatic β-cell mass with [11C] DTBZ


NR Simpson, F Souza, P Witkowski, A Maffei, … - Nuclear medicine and biology, 2006 - Elsevier
Type 1 diabetes (T1D) is a result of the autoimmune destruction of the
insulin-producing β cells of the islets of Langerhans—the endocrine component
of the pancreas [2]. This disease has an insipid beginning and may take ...
Cited by 26 - Related articles - All 5 versions

GAD treatment and insulin secretion in recent-onset type 1 diabetes


J Ludvigsson, M Faresjo, M Hjorth, S … - The New England journal of medicine, 2008 - nejm.highwire.org
Results Insulin secretion gradually decreased in both study groups. The study
treatment had no significant effect on change in fasting C-peptide level after
15 months (the primary end point). Fasting C-peptide levels declined from ...
Cited by 29 - Related articles - All 7 versions

Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB …


GS Wang, L Rosenberg, FW Scott - Laboratory Investigation, 2005 - nature.com
Tubular complexes (TC) in the pancreas contain duct-like structures with low
cuboidal or flattened cells surrounding a large lumen and are thought to be a
response to pancreatic injury. TC have been studied in animal models of ...
Cited by 22 - Related articles - All 3 versions

Reduction of early graft loss after intraportal porcine islet transplantation in monkeys


PPM Rood, R Bottino, AN Balamurugan, C … - Transplantation, 2007 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 22 - Related articles - BL Direct - All 3 versions

Current progress in non-invasive imaging of beta cell mass of the endocrine pancreas

- bentham.org [PDF] 
F Souza, M Freeby, K Hultman, N Simpson, A … - Current medicinal chemistry, 2006 - ingentaconnect.com
1 Department of Medicine, Columbia University Medical Center, New York, NY
10032, USA 2 Department of Applied Physics and Applied Mathematics, Columbia
University, New York, NY 10032, USA 3 Department of Radiology, Columbia ...
Cited by 20 - Related articles - BL Direct - All 7 versions

Thirty years of investigating the autoimmune basis for type 1 diabetes

- shouxi.net
MA Atkinson - Diabetes, 2005 - Am Diabetes Assoc
Thirty years ago, a convergence of investigational observations lead to the now
widely accepted notion that type 1 diabetes results from an autoimmune
destruction of insulin-producing β-cells in subjects genetically ...
Cited by 19 - Related articles - All 9 versions


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