- ►cell.com KA Moynihan, AA Grimm, MM Plueger, E Bernal- … - Cell Metabolism, 2005 - Elsevier Sir2 NAD-dependent deacetylases connect transcription, metabolism, and aging. Increasing
the dosage or activity of Sir2 extends life span in yeast, worms, and flies and promotes fat mobilization
and glucose production in mammalian cells. Here we show that increased dosage of ... Cited by 137 - Related articles - All 18 versions
- ►diabetesjournals.org KM Utzschneider, DB Carr, RL Hull, K Kodama, JB … - Diabetes, 2004 - Am Diabetes Assoc The prevalence of glucose intolerance and type 2 diabetes increases with age. To determine
whether the hyperbolic relationship between insulin sensitivity and the insulin response is affected
by age and whether the decline in β-cell function with age is related to increases in intra- ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org A Sakima, DB Averill, PE Gallagher, SO Kasper, EN … - Hypertension, 2005 - Am Heart Assoc Age-related baroreflex reductions in function may originate from central neural dysregulation
as well as vascular structural/functional changes. We determined the role of 2 angiotensin
(Ang) peptides at the nucleus tractus solitarii in age-related baroreflex impairment. ... Cited by 30 - Related articles - All 7 versions
- ►diabetesjournals.org K Maedler, DM Schumann, F Schulthess, J Oberholzer, … - Diabetes, 2006 - Am Diabetes Assoc Type 2 diabetes is characterized by a deficit in β-cell mass, and its incidence increases with
age. Here, we analyzed β-cell turnover in islets from 2- to 3- compared with 7- to 8-month-old
rats and in human islets from 53 organ donors with ages ranging from 17 to 74 years. In ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►physiology.org SO Kasper, CS Carter, CM Ferrario, D … - Physiological …, 2005 - Am Physiological Soc Transgenic rats with targeted decreased glial expression of angiotensinogen (ASrAogen
rats) did not show an increase in systolic pressure compared with Sprague-Dawley (SD) rats
during aging (15–69 wk of age). ASrAogen animals had lower body weights throughout ... Cited by 21 - Related articles - All 5 versions
DY Kwon, JS Jang, SM Hong, JE Lee, SR Sung, … - European Journal of …, 2007 - Springer DY Kwon Food Functional Research Division Korean Food Research Institutes Seoul, Korea
JS Jang Æ SM Hong Æ JE Lee Æ SR Sung HR Park Æ S. Park, PhD (&) Dept. of Food and Nutrition
Institute of Basic Sciences Hoseo University 165 Sechul-Ri Baebang-Myun Asan-Si ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►physiology.org S Gilliam-Davis, VS Payne, SO Kasper, … - American Journal of …, 2007 - Am Physiological Soc Fischer-344 (F344) rats exhibit proteinuria and insulin resistance in the absence of hypertension
as they age. We determined the effects of long-term (1 yr) treatment with the angiotensin
(ANG) II type 1 (AT 1 ) receptor blocker L-158,809 on plasma and urinary ANG peptide ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►endojournals.org S Park, SM Hong, SR Sung, HK Jung - Endocrinology, 2008 - Endocrine Soc To determine the long-term effect of central leptin and resistin on energy homeostasis, peripheral
insulin resistance, and β-cell function and mass, intracerebroventricular (ICV) infusion of leptin
(3 ng/h), resistin (80 ng/h), leptin plus resistin, and cerebrospinal fluid (control) was ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►liptapro.net [PDF] RH Muzumdar, X Ma, X Yang, G Atzmon, N Barzilai - Neurobiology of Aging, 2006 - Elsevier Aging is associated with resistance to the effects of leptin on food intake and energy
homeostasis. We examined if old rats were resistant to the effects of leptin on glucose stimulated
insulin secretion. When leptin was infused intravenously (0.5 μg/kg/min) under ... Cited by 7 - Related articles - All 21 versions
