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Scholar Results 1 - 10 of about 15 citing Pezzolesi: Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibil.... (0.10 sec) 

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains
differ in the response of their critical physiological functions, such as insulin sensitivity, ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels …

- gemstudy.ca [PDF] 
Y Yu, DF Wyszynski, DM Waterworth, SD Wilton, … - Science's …, 2005 - stke.sciencemag.org
Abstract: We conducted a genome-wide scan using variance components linkage analysis to
localize quantitative-trait loci (QTLs) influencing triglyceride (TG), high density lipoprotein-cholesterol
(HDL-C), low density lipoprotein-cholesterol, and total cholesterol (TC) levels in 3,071 ...
Cited by 23 - Related articles - BL Direct - All 7 versions

Identification of a locus for maturity-onset diabetes of the young on chromosome …


SH Kim, X Ma, S Weremowicz, T Ercolino, C Powers, W … - Diabetes, 2004 - Am Diabetes Assoc
Maturity-onset diabetes of the young (MODY) is a subtype of diabetes defined by an autosomal
dominant inheritance and a young onset. Six MODY genes have been discovered to date. To
identify additional MODY loci, we conducted a genome scan in 21 extended US families ...
Cited by 19 - Related articles - BL Direct - All 5 versions

Association of single-nucleotide polymorphisms in the suppressor of cytokine …

- tokushima-u.ac.jp [PDF] 
H Kato, K Nomura, D Osabe, S Shinohara, O Mizumori, … - Genomics, 2006 - Elsevier
Several previous linkage scans in type 2 diabetes (T2D) families indicated a putative susceptibility
locus on chromosome 12q15–q22, while the underlying gene for T2D has not yet been
identified. We performed a region-wide association analysis on 12q15–q22, using a ...
Cited by 19 - Related articles - All 5 versions

Linkage and association studies of the susceptibility genes for type 2 diabetes

- jgenetgenomics.org [PDF] 
QY HUANG, MR CHENG, SL JI - Acta Genetica Sinica, 2006 - Elsevier
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by hyperglycemia, insulin
resistance, and impaired insulin secretion. T2DM is under strong genetic control. Identification
and characterization of genes involved in determining T2DM will contribute to a greater ...
Cited by 10 - Related articles - All 3 versions

Identification of a chromosome 8p locus for early-onset coronary heart disease in a …


JC Engert, M Lemire, J Faith, D Brisson, TM … - European Journal of …, 2007 - nature.com
Susceptibility to coronary heart disease (CHD) has long been known to exhibit familial
aggregation, with heritability estimated to be greater than 50%. The French Canadian population
of the Saguenay-Lac Saint-Jean region of Quebec, Canada is descended from a founder ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Genetic association of single nucleotide polymorphisms in endonuclease G-like 1 …

- tokushima-u.ac.jp [PDF] 
M Moritani, K Nomura, T Tanahashi, D Osabe, Y Fujita, … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Genetic association of single nucleotide polymorphisms in endonuclease
G-like 1 gene with type 2 diabetes in a Japanese population M. Moritani & K. Nomura & T.
Tanahashi & D. Osabe & Y. Fujita & S. Shinohara & Y. Yamaguchi & P. Keshavarz & ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Isolation and functional analysis of human HMBOX1, a homeobox containing …


S Chen, H Saiyin, X Zeng, J Xi, X Liu, X Li, L … - Cytogenet Genome …, 2006 - content.karger.com
We have identified and isolated a novel human gene, HMBOX1 (homeobox containing 1) from
a pancreatic cDNA library. Human HMBOX1 is widely expressed in 18 tissues, and it is highly
expressed in pancreas. According to the genome database, HMBOX1 is located at the ...
Cited by 4 - Related articles - BL Direct - All 5 versions

2 型糖尿病易感基因的连锁和关联研究


黄青阳, 程孟荣, 姬森林 - 遗传学报, 2006 - cqvip.com
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维普资讯 中文期刊·专业文章. 维普专业检索Google学术. 生物学 >> 遗传学报 >> 2006年33卷7期 >>
摘要. 2型糖尿病易感基因的连锁和关联研究. 评论推荐. 下载全文. 黄青阳[1,2] 程孟荣[1] 姬森林 ...
Cited by 8 - Related articles - All 3 versions

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY …


JS Dunn, WM Mlynarski, MG Pezzolesi, M … - Annals of Human …, 2006 - interscience.wiley.com
The product of the PPP1R3B gene (G L ) is the regulatory subunit of PP1 - a serine/threonine
phosphatase involved in the modulation of glycogen synthesis in the liver and skeletal
muscle. The PPP1R3B gene is located on chromosome 8p23 in a region that has been ...
Cited by 2 - Related articles - BL Direct - All 3 versions


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