- ►nih.gov N Tiffin, E Adie, F Turner, HG Brunner, MA van … - Nucleic acids …, 2006 - Oxford Univ Press Genome-wide experimental methods to identify disease genes, such as linkage analysis and association
studies, generate increasingly large candidate gene sets for which comprehensive empirical analysis
is impractical. Computational ... Cited by 48 - Related articles - BL Direct - All 20 versions
- ►pubget.com [PDF] SC Elbein, WS Chu, SK Das, A Yao-Borengasser, SJ … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis We sought to determine: (1) the role of previously described transcription
factor 7-like 2 (TCF7L2) variants in type 2 diabetes in African American individuals and in
participants of European ancestry; ... Cited by 31 - Related articles - BL Direct - All 6 versions
YH Hamid, SA Urhammer, DP Jensen, C Glümer, K … - Diabetes, 2004 - Am Diabetes Assoc Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the pathophysiology of various human
diseases such as type 2 diabetes and obesity. IL-6 signals via a heterodimeric receptor complex
consisting of a soluble IL-6 ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►endojournals.org H Wang, Z Zhang, W Chu, T Hale, JJ Cooper, … - Journal of Clinical …, 2005 - Endocrine Soc IL-6 levels and polymorphisms have been implicated in type 2 diabetes mellitus (T2DM) and insulin
resistance. The IL-6 receptor (IL-6R) comprises two subunits, IL-6R and gp130, of which IL-6R
confers specificity to IL-6 action ... Cited by 28 - Related articles - All 5 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains differ in
the response of their critical ... Cited by 29 - Related articles - BL Direct - All 4 versions
SK Das, SC Elbein - Cellscience, 2006 - pubmedcentral.nih.gov Type 2 Diabetes results from a complex physiologic process that includes the pancreatic beta cells,
peripheral glucose uptake in muscle, the secretion of multiple cytokines and hormone-like molecules
from adipocytes, hepatic glucose ... Cited by 25 - Related articles - All 3 versions
- ►hematologylibrary.org [PDF] F Groot, S Welsch, QJ Sattentau - Blood, 2008 - bloodjournal.hematologylibrary.org . Hematology; all rights reserved Copyright 2007 by The American Society of DC 20036. by the
American Society of Hematology, 1900 M St, NW, Suite 200, Washington Blood (print ISSN 0006-4971,
online ISSN 1528-0020), is ... Cited by 17 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org SK Das, W Chu, Z Zhang, SJ Hasstedt, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc Genome-wide scans in multiple populations have identified chromosome 1q21-q24 as one susceptibility
region for type 2 diabetes. To map the susceptibility genes, we first placed a dense single
nucleotide polymorphism (SNP) map ... Cited by 14 - Related articles - BL Direct - All 4 versions
GA Hitman, J Sudagani - International Journal of Clinical …, 2004 - interscience.wiley.com Evidence for a genetic basis for type 2 diabetes and the metabolic syndrome has been derived from
studies of families, twins and populations with genetic admixture. Identification of genes
associated with disease ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org E Zeggini, CM Damcott, RL Hanson, MA Karim, NW … - Diabetes, 2006 - Am Diabetes Assoc The gene encoding the transcription factor upstream stimulatory factor (USF)1 influences
susceptibility to familial combined hyperlipidemia (FCHL) and triglyceride levels. Phenotypic
overlap between FCHL and type 2 ... Cited by 17 - Related articles - BL Direct - All 7 versions
